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2.3.1.16: acetyl-CoA C-acyltransferase

This is an abbreviated version!
For detailed information about acetyl-CoA C-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.16

Reaction

acyl-CoA
+
acetyl-CoA
=
CoA
+
3-oxoacyl-CoA

Synonyms

2-enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-oxoacyl-CoA thiolase, 3-KAT, 3-ketoacyl CoA thiolase, 3-ketoacyl coenzyme A thiolase, 3-ketoacyl coenzyme-A thiolase, 3-ketoacyl thiolase, 3-ketoacyl-CoA thiolase, 3-ketothiolase, 3-oxoacyl-CoA thiolase, 3-oxoacyl-coenzyme A thiolase, 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase, 6-oxoacyl-CoA thiolase, ACAA2, acetoacetyl-CoA beta-ketothiolase, acetyl-CoA acyltransferase, acyl-CoA-thiolase, acyltransferase, acetyl coenzyme A, beta-ketoacyl coenzyme A thiolase, beta-ketoacyl-CoA thiolase, beta-ketoadipyl coenzyme A thiolase, beta-ketoadipyl-CoA thiolase, beta-ketothiolase, BktB, ELo1, Elovl-5, Elovl-6, ELOVL5, Elovl6, enoyl-coenzyme A (CoA) hydratase/3-hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase trifunctional protein, FadA, fatty acid elongase 5, KAT, KAT-1, KAT2, ketoacyl-CoA acyltransferase, ketoacyl-coenzyme A thiolase, long-chain 3-oxoacyl-CoA thiolase, mitochondrial 3-ketoacyl-CoA thiolase, oxoacyl-coenzyme A thiolase, PaaJ, pro-3-ketoacyl-CoA thiolase, PUFA elongase, SCP2/3-oxoacyl-CoA thiolase, SCPx, sterol carrier protein 2/3-oxoacyl-CoA thiolase, TFE-beta subunit, Thb, thiloase B, thiolase A, thiolase I, thiolase II, thiolase III

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.16 acetyl-CoA C-acyltransferase

Cloned

Cloned on EC 2.3.1.16 - acetyl-CoA C-acyltransferase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
3-ketoacyl-CoA thiolase A and B
DNA and amino acid sequence determination, expression analysis
-
expression in Eescherichia coli
expression in Escherichia coli
expression in Escherichia coli of a full-length and truncated version
-
expression in Saccharomyces cerevisiae
-
expression of a His-tagged truncated enzyme lacking the N-terminal peroxisomal targeting sequence of 34 amino acid residues in Escherichia coli strain BL21(DE3)
expression of KAT gene on chromosome 2 mutant lacking the putative N-terminal peroxisomal targeting sequence in Escherichia coli
gene ACAA2, recombinant expression of His-tagged wild-type and mutant enzymes in Escherichia coli strain BL21(DE3)
His-tagged wild-type and His352 mutant proteins overexpressed in Escherichia coli
-
recombinant expression of tagged enzyme
-