2.3.1.15: glycerol-3-phosphate 1-O-acyltransferase

This is an abbreviated version!
For detailed information about glycerol-3-phosphate 1-O-acyltransferase, go to the full flat file.

Reaction

Synonyms

1-acyl-sn-glycerol-3-phosphate acyltransferase, 3-glycerophosphate acyltransferase, ACP:sn-glycerol-3-phosphate acyltransferase, acyl-CoA:glycerol-3-phosphate acyltransferase 1, acyl-CoA:sn-glycerol-3-phosphate O-acyltransferase, acyl-[acyl carrier protein]:sn-1-glycerol-3-phosphate acyltransferase, acyltransferase, glycerol phosphate, Ad-GPAT1, AGPAT, AGPAT10, AGPAT6, AGPAT8, AGPAT9, alpha-glycerophosphate acyltransferase, AT1G02390, AT1G06520, AT3G11430, AT4G00400, AT4G01950, AT5G06090, AT5G60620, AtGPAT1, AtGPAT2, AtGPAT3, AtGPAT5, AtGPAT7, AtGPAT8, AtGPAT9, cancer-testicular antigen, chloroplast glycerol-3-phosphate acyltransferase, CrGAPTcl, ER-associated GPAT, G3P acyltransferase, GAT, Gat1, GAT1p, GAT2p, glycerol 3-phosphate acyltransferase, glycerol phosphate acyltransferase, glycerol phosphate transacylase, glycerol-3-P acyltransferase 1, glycerol-3-phosphate acyltransferase, glycerol-3-phosphate acyltransferase 1, glycerol-3-phosphate acyltransferase 2, glycerol-3-phosphate acyltransferase 3, glycerol-3-phosphate acyltransferase 4, glycerol-3-phosphate acyltransferase 9, glycerol-3-phosphate acyltransferase-1, glycerol-3-phosphate acyltransferase-like protein 1, glycerol-3-phosphate O-acyltransferase, glycerol-3-phosphate-1 acyltransferase, glycerol-sn-3-phosphate acyltransferase 1, glycerophosphate acyltransferase, glycerophosphate transacylase, GPAM, GPAT, GPAT-1, GPAT-4, GPAT-9, GPAT1, GPAT2, GPAT3, GPAT3/AGPAT10, GPAT4, GPAT5, GPAT6, GPAT7, GPAT8, GPAT9, gpt1, Gpt2, LeGPAT, LiGPAT, LPAAT-theta, LPAAT-zeta, mGPAT, microsomal GPAT3, microsomal GPAT3/AGPAT10, microsomal GPAT4, mitochondrial glycerol-3-phosphate acyltransferase, mitochondrial GPAT1, mitochondrial GPAT2, More, MS33, mtGPAT, mtGPAT1, mtGPAT2, OsGPAT3, PHATRDRAFT_42446, PHYPADRAFT_137573, PLAT2, PlsB, PlsB1, Ppa GPAT9, PpGPAT9, PtGPAT, Rv1551, Rv1551 acyltransferase, SA1, Sn-glycerol 3-phosphate acyltransferase, sn-glycerol-3-phosphate acyltransferase, SsGPAT, TbGAT, water-soluble plastidial glycerol-3-phosphate acyltransferase, xGPAT1, xGPAT1-v1, xGPAT1-v2

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.15 glycerol-3-phosphate 1-O-acyltransferase

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Results	in table
70	Activating Compound
10497	AA Sequence
14	Application
1	CAS Registry Number
73	Cloned(Commentary)
1	Cofactor
5	Crystallization (Commentary)
280	Disease/ Diagnostics
9	Expression
156	General Information
17	General Stability
43	IC50 Value
196	Inhibitors
4	kcat/KM [mM/s]
16	Ki Value [mM]
114	KM Value [mM]
206	Localization
40	Metals/Ions
43	Molecular Weight [Da]
87	Natural Substrates/ Products (Substrates)
1933	Organism
15	Pathway
2	PDB ID
41	pH Optimum
5	pH Range
1	pI Value
9	Posttranslational Modification
48	Protein Variants
59	Purification (Commentary)
4	Reaction
16	Reaction Type
199	Reference
16	Renatured (Commentary)
326	Source Tissue
61	Specific Activity [micromol/min/mg]
17	Storage Stability
472	Substrates and Products (Substrate)
30	Subunits
345	Synonyms
1	Systematic Name
25	Temperature Optimum [°C]
2	Temperature Range [°C]
2	Temperature Stability [°C]
4	Turnover Number [1/s]

IC50 Value

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of the Enzyme Summary Page.

IC50 Value on EC 2.3.1.15 - glycerol-3-phosphate 1-O-acyltransferase

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.295

(+-)-2-(2-hydroxy-3-(octylsulfonamido)-cyclopentyl)acetic acid

Homo sapiens

-

pH not specified in the publication, temperature not specified in the publication

719080

0.164

(+-)-2-hydroxy-3-(octylsulfonamido)-cyclohexanecarboxylic acid

Homo sapiens

-

pH not specified in the publication, temperature not specified in the publication

719080

0.255

(+-)-2-hydroxy-3-(octylsulfonamido)-cyclopentane carboxylic acid

Homo sapiens

-

pH not specified in the publication, temperature not specified in the publication

719080

0.324

(+-)-2-hydroxy-3-(octylsulfonamido)-cyclopentanecarboxylic acid

Homo sapiens

-

pH not specified in the publication, temperature not specified in the publication

719080

0.152

2-(2-phenylethylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.107

2-(4-chlorophenylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.0183

2-(hexadecylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.132

2-(methylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.0247

2-(nonylsulfonamido)benzoic acid

2 entries

0.0811

2-(nonylsulfonamido)benzylphosphonic acid

Homo sapiens

-

-

705036

0.0736

2-(octylsulfonamido)phenylphosphonic acid

Homo sapiens

-

-

705036

0.129

2-(pentylsulfonamido)benzylphosphonic acid

Homo sapiens

-

-

705036

0.14

2-(phenylmethylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.146

2-(phenylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.0174

2-(tetradecylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.164

3-(2-phenylethylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.0757

3-(4-chlorophenylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.0739

3-(nonylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.0628

3-(nonylsulfonamido)benzylphosphonic acid

Homo sapiens

-

-

705036

0.0835

3-(nonylsulfonamidomethyl)benzoic acid

Homo sapiens

-

-

705036

0.0724

3-(octylsulfonamido)phenylphosphonic acid

Homo sapiens

-

-

705036

0.141

3-(pentylsulfonamido)benzylphosphonic acid

Homo sapiens

-

-

705036

0.31

3-(pentylsulfonamidomethyl)benzoic acid

Homo sapiens

-

-

705036

0.178

3-(phenylmethylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.138

3-(phenylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.206

4-(2-phenylethylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.108

4-(4-chlorophenylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.0889

4-(nonylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.0813

4-(nonylsulfonamido)benzylphosphonic acid

Homo sapiens

-

-

705036

0.0665 - 0.129

4-(nonylsulfonamidomethyl)benzoic acid

2 entries

0.0953

4-(octylsulfonamido)phenylphosphonic acid

Homo sapiens

-

-

705036

0.148

4-(pentylsulfonamido)benzylphosphonic acid

Homo sapiens

-

-

705036

0.217 - 0.252

4-(pentylsulfonamidomethyl)benzoic acid

2 entries

0.221

4-(phenylmethylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.151

4-(phenylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.0318

5-chloro-2-(nonylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.089

5-fluoro-2-(octylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.116

5-hydroxy-2-(octylsulfonamido)benzoic acid

Homo sapiens

-

-

705036

0.0945 - 0.126

palmitoyl-CoA

2 entries

0.0247

2-(nonylsulfonamido)benzoic acid

Homo sapiens

-

demonstrates the greatest inhibitory activity

705036

0.0247

2-(nonylsulfonamido)benzoic acid

Homo sapiens

-

pH not specified in the publication, temperature not specified in the publication

719080

0.0665

4-(nonylsulfonamidomethyl)benzoic acid

Homo sapiens

-

-

705036

0.129

4-(nonylsulfonamidomethyl)benzoic acid

Homo sapiens

-

-

705036

0.217

4-(pentylsulfonamidomethyl)benzoic acid

Homo sapiens

-

-

705036

0.252

4-(pentylsulfonamidomethyl)benzoic acid

Homo sapiens

-

-

705036

0.0945

palmitoyl-CoA

Rattus norvegicus

-

with addition of insulin

702011

0.126

palmitoyl-CoA

Rattus norvegicus

-

without addition of insulin

702011