2.3.1.148: glycerophospholipid acyltransferase (CoA-dependent)
This is an abbreviated version!
For detailed information about glycerophospholipid acyltransferase (CoA-dependent), go to the full flat file.
Reaction
Synonyms
Acylcoenzyme A acyltransferase
ECTree
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Substrates Products
Substrates Products on EC 2.3.1.148 - glycerophospholipid acyltransferase (CoA-dependent)
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REACTION DIAGRAM
1-Acyl-2-arachidonoyl-glycerophosphocholine + lyso-phosphatidylethanolamine
1-Acyl-2-lyso-glycerophosphocholine + arachidonoylphosphatidylethanolamine
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transfer of arachidonate occurs through a bidirectional movement
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-
?
1-acyl-2-arachidonoyl-sn-glycero-3-phosphoinositol + lyso-phosphatidylcholine
1-acyl-2-lyso-sn-glycero-3-phosphoinositol + ?
-
-
-
-
?
1-Acyl-2-arachidonoyl-sn-glycero-3-phosphophoinositol + lyso-phosphatidylethanolamine
1-Acyl-2-lyso-sn-glycero-3-phosphoinositol + arachidonoylphosphatidylethanolamine
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unidirectional transfer process of arachidonate
-
-
?
1-acyl-2-lyso-glycerophosphocholine + arachidonoylphosphatidylethanolamine
1-acyl-2-arachidonoyl-glycerophosphocholine + lyso-phosphatidylethanolamine
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-
-
-
r
1-palmitoyl-2-lyso-glycerophosphocholine + arachidonoylphosphatidylethanolamine
1-palmitoyl-2-arachidonoyl-glycerophosphocholine + lyso-phosphatidylethanolamine
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-
-
-
r
lyso-Phosphatidylethanolamine + phospholipid
Phosphatidylethanolamine + lyso-phospholipid
-
-
-
-
?
lyso-Phosphatidylinositol + phospholipid
Phosphatidylinositol + lyso-phospholipid
-
-
-
-
?
lyso-Phosphatidylserine + phospholipid
Phosphatidylserine + lyso-phospholipid
-
-
-
-
?
Phosphatidylcholine + lyso-phosphatidylethanolamine
lyso-Phosphatidylcholine + phosphatidylethanolamine
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-
-
-
?
Phosphatidylcholine + lyso-phosphatidylinositol
lyso-Phosphatidylcholine + phosphatidylinositol
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the linoleoyl transfer takes place at about 25% of the rate of arachidonoyl transfer
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-
?
Phosphatidylinositol + lyso-phosphatidylcholine
lyso-Phosphatidylcholine + phosphatidylinositol
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the linoleoyl transfer takes place at about 25% of the rate of arachidonoyl transfer
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-
?
?
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more efficient transfer of arachidonate from phosphatidylcholine to the ethanolamine-containing phospholipids than from phosphatidylinositol
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-
?
additional information
?
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arachidonate and linoleate at the sn-2 position of phosphatidylcholine can be transferred to lyso-phosphatidylethanolamine. The transfer of 16:0, 18:0, and 18:1 acyl moieties at the sn-2-position of phosphatidylcholine is negligible
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?