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2.3.1.147: glycerophospholipid arachidonoyl-transferase (CoA-independent)

This is an abbreviated version!
For detailed information about glycerophospholipid arachidonoyl-transferase (CoA-independent), go to the full flat file.

Word Map on EC 2.3.1.147

Reaction

1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine
+
1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine
=
1-organyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine
 +
1-organyl-2-lyso-sn-glycero-3-phosphocholine

Synonyms

Acyltransferase, 1-alkylglycerophosphocholine, CoA-independent transacylase, CoA-IT, CoAIT, Coenzyme A-independent transacylase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.147 glycerophospholipid arachidonoyl-transferase (CoA-independent)

Reference

topprint

Reference on EC 2.3.1.147 - glycerophospholipid arachidonoyl-transferase (CoA-independent)

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Winkler, J.D.; Sung, C.M.; Marshall, L.A.; Chilton, F.H.
Inhibitors of arachidonate metabolism and effects on PAF production
Adv. Exp. Med. Biol.
416
11-45
1996
Homo sapiens
Manually annotated by BRENDA team
Winkler, J.D.; Eris, T.; Sung, C.M.; Chabot-Fletcher, M.; Mayer, R.J.; Surette, M.E.; Chilton, F.H.
Inhibitors of coenzyme A-independent transacylase induce apoptosis in human HL-60 cells
J. Pharmacol. Exp. Ther.
279
956-966
1996
Homo sapiens
Manually annotated by BRENDA team
Yamashita, A.; Sugiura, T.; Waku, K.
Acyltransferases and transacylases involved in fatty acid remodeling of phospholipids and metabolism of bioactive lipids in mammalian cells
J. Biochem.
122
1-16
1997
Homo sapiens, Mammalia
Manually annotated by BRENDA team
Winkler, J.D.; Sung, C.M.; Chabot-Flecher, M.; Griswold, D.E.; Marshall, L.A.; Chilton, F.H.; Bondinell, W.; Mayer, R.J.
beta-Lactams SB 212047 and SB 216754 are irreversible, time-dependent inhibitors of coenzyme A-independent transacylase
Mol. Pharmacol.
53
322-329
1998
Homo sapiens
Manually annotated by BRENDA team
Winkler, J.D.; Fonteh, A.N.; Sung, C.M.; Heravi, J.D.; Nixon, A.B.; Chabot-Fletcher, M.; Griswold, D.; Marshall, L.A.; Chilton, F.H.
Effects of CoA-independent transacylase inhibitors on the production of lipid inflammatory mediators
J. Pharmacol. Exp. Ther.
274
1338-1347
1995
Homo sapiens
Manually annotated by BRENDA team
Chilton, F.H.; Fonteh, A.N.; Sung, C.M.; Hickey, D.M.B.; Torphy, T.J.; Mayer, R.J.; Marshall, L.A.; Heravi, J.D.; Winkler, J.D.
Inhibitors of CoA-independent transacylase block the movement of arachidonate into 1-ether-linked phospholipids of human neutrophils
Biochemistry
34
5403-5410
1995
Homo sapiens
Manually annotated by BRENDA team
Toyoshima, K.; Narahara, H.; Frenkel, R.A.; Johnston, J.M.
Coenzyme A-independent transacylation in amnion-derived (WISH) cells
Arch. Biochem. Biophys.
314
224-228
1994
Homo sapiens
Manually annotated by BRENDA team
Winkler, J.D.; Sung, C.M.; Bennett, C.F.; Chilton, F.H.
Characterization of CoA-independent transacylase activity in U937 cells
Biochim. Biophys. Acta
1081
339-346
1991
Homo sapiens
Manually annotated by BRENDA team
Robinson, M.; Blank, M.L.; Snyder, F.
Acylation of lysophospholipids by rabbit alveolar macrophages
J. Biol. Chem.
260
7889-7895
1985
Oryctolagus cuniculus
Manually annotated by BRENDA team
Svetlov, S.I.; Liu, H.; Chao, W.; Olson, M.S.
Regulation of platelet-activating factor (PAF) biosynthesis via coenzyme A-independent transacylase in the macrophage cell line IC-21 stimulated with lipopolysaccharide
Biochim. Biophys. Acta
1346
120-130
1997
Mus musculus
Manually annotated by BRENDA team
Neville, N.T.; Parton, J.; Harwood, J.L.; Jackson, S.K.
The activities of monocyte lysophosphatidylcholine acyltransferase and coenzyme A-independent transacylase are changed by the inflammatory cytokines tumor necrosis factor alpha and interferon gamma
Biochim. Biophys. Acta
1733
232-238
2005
Homo sapiens
Manually annotated by BRENDA team
Trimboli, A.J.; Waite, B.M.; Atsumi, G.I.; Fonteh, A.N.; Namen, A.M.; Clay, C.E.; Kute, T.E.; High, K.P.; Willingham, M.C.; Chilton, F.H.
Influence of coenzyme A-independent transacylase and cyclooxygenase inhibitors on the proliferation of breast cancer cells
Cancer Res.
59
6171-6177
1999
Homo sapiens
Manually annotated by BRENDA team
Monjazeb, A.M.; High, K.P.; Koumenis, C.; Chilton, F.H.
Inhibitors of arachidonic acid metabolism act synergistically to signal apoptosis in neoplastic cells
Prostaglandins Leukot. Essent. Fatty Acids
73
463-474
2005
Homo sapiens
Manually annotated by BRENDA team
Seeds, M.C.; Peachman, K.K.; Bowton, D.L.; Sivertson, K.L.; Chilton, F.H.
Regulation of arachidonate remodeling enzymes impacts eosinophil survival during allergic asthma
Am. J. Respir. Cell Mol. Biol.
41
358-366
2009
Homo sapiens
Manually annotated by BRENDA team
Astudillo, A.M.; Perez-Chacon, G.; Balgoma, D.; Gil-de-Gomez, L.; Ruiperez, V.; Guijas, C.; Balboa, M.A.; Balsinde, J.
Influence of cellular arachidonic acid levels on phospholipid remodeling and CoA-independent transacylase activity in human monocytes and U937 cells
Biochim. Biophys. Acta
1811
97-103
2011
Homo sapiens
Manually annotated by BRENDA team