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2.3.1.147: glycerophospholipid arachidonoyl-transferase (CoA-independent)

This is an abbreviated version!
For detailed information about glycerophospholipid arachidonoyl-transferase (CoA-independent), go to the full flat file.

Word Map on EC 2.3.1.147

Reaction

1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine
+
1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine
=
1-organyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine
+
1-organyl-2-lyso-sn-glycero-3-phosphocholine

Synonyms

Acyltransferase, 1-alkylglycerophosphocholine, CoA-independent transacylase, CoA-IT, CoAIT, Coenzyme A-independent transacylase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.147 glycerophospholipid arachidonoyl-transferase (CoA-independent)

Application

Application on EC 2.3.1.147 - glycerophospholipid arachidonoyl-transferase (CoA-independent)

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
medicine
-
disruption of arachidonic acid remodeling in a manner that increases intracellular arachidonic acid level involving inhibition of the enzyme may represent a novel therapeutic strategy to reduce cancer cell proliferation
pharmacology
-
the enzyme may be a new therapeutic target to regulate inflammatory mediators