2.3.1.13: glycine N-acyltransferase

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For detailed information about glycine N-acyltransferase, go to the full flat file.

Reaction

Synonyms

acyltransferase, glycine, GlyAT, GLYATL1, GLYATL2, GLYATL3, glycine acyltransferase, glycine N-acyltransferase, glycine N-acyltransferase-like 3, glycine-N-acylase, glycine-N-acyltransferase, glycine-N-acyltransferase like 1

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.13 glycine N-acyltransferase

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Results	in table
15	AA Sequence
2	Application
6	Cloned(Commentary)
45	Disease/ Diagnostics
2	Expression
4	General Information
2	General Stability
2	IC50 Value
29	Inhibitors
11	kcat/KM [mM/s]
6	Ki Value [mM]
63	KM Value [mM]
11	Localization
6	Metals/Ions
12	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
28	Organism
5	PDB ID
6	pH Optimum
1	pH Range
1	pI Value
22	Protein Variants
11	Purification (Commentary)
3	Reaction
27	Reference
39	Source Tissue
11	Specific Activity [micromol/min/mg]
2	Storage Stability
70	Substrates and Products (Substrate)
13	Subunits
19	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
11	Turnover Number [1/s]

Expression

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Expression on EC 2.3.1.13 - glycine N-acyltransferase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

isoform Glyat expression is suppressed in all hepatocellular carcinomas, but not in other liver diseases. Glyat repression in cancerous cells in the liver is controlled at the transcriptional level

Homo sapiens

Q6IB77

718757

the enzyme is overexpressed in primary prostate cancer compared with metastatic prostate cancer and benign prostatic tissue. Low-grade cancers have higher enzyme expression compared to high-grade prostate tumors

Homo sapiens

-

758269