2.3.1.13: glycine N-acyltransferase

This is an abbreviated version!
For detailed information about glycine N-acyltransferase, go to the full flat file.

Reaction

Synonyms

acyltransferase, glycine, GlyAT, GLYATL1, GLYATL2, GLYATL3, glycine acyltransferase, glycine N-acyltransferase, glycine N-acyltransferase-like 3, glycine-N-acylase, glycine-N-acyltransferase, glycine-N-acyltransferase like 1

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.13 glycine N-acyltransferase

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Results	in table
15	AA Sequence
2	Application
6	Cloned(Commentary)
45	Disease/ Diagnostics
2	Expression
4	General Information
2	General Stability
2	IC50 Value
29	Inhibitors
11	kcat/KM [mM/s]
6	Ki Value [mM]
63	KM Value [mM]
11	Localization
6	Metals/Ions
12	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
28	Organism
5	PDB ID
6	pH Optimum
1	pH Range
1	pI Value
22	Protein Variants
11	Purification (Commentary)
3	Reaction
27	Reference
39	Source Tissue
11	Specific Activity [micromol/min/mg]
2	Storage Stability
70	Substrates and Products (Substrate)
13	Subunits
19	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
11	Turnover Number [1/s]

Disease

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Disease on EC 2.3.1.13 - glycine N-acyltransferase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Breast Neoplasms

Downregulation of GLYAT Facilitates Tumor Growth and Metastasis and Poor Clinical Outcomes Through the PI3K/AKT/Snail Pathway in Human Breast Cancer.

33968740

Carcinogenesis

Designation of enzyme activity of glycine-N-acyltransferase family genes and depression of glycine-N-acyltransferase in human hepatocellular carcinoma.

22475485

Carcinoma, Hepatocellular

Designation of enzyme activity of glycine-N-acyltransferase family genes and depression of glycine-N-acyltransferase in human hepatocellular carcinoma.

22475485

Carcinoma, Hepatocellular

The expression and prognostic value of GLYATL1 and its potential role in hepatocellular carcinoma.

33457003

Hyperglycinemia, Nonketotic

Glycine and benzoate conjugation and glycine acyltransferase activity in the developing and adult rat: possible relationships to nonketotic hyperglycinemia.

7338122

Metabolism, Inborn Errors

Frequent sequence variants of human glycine N-acyltransferase (GLYAT) and inborn errors of metabolism.

33567294

Neoplasm Metastasis

Downregulation of GLYAT Facilitates Tumor Growth and Metastasis and Poor Clinical Outcomes Through the PI3K/AKT/Snail Pathway in Human Breast Cancer.

33968740

Neoplasms

Characterization of glycine-N-acyltransferase like 1 (GLYATL1) in prostate cancer.

31376196

Neoplasms

Downregulation of GLYAT Facilitates Tumor Growth and Metastasis and Poor Clinical Outcomes Through the PI3K/AKT/Snail Pathway in Human Breast Cancer.

33968740

Neoplasms

Glycine conjugation: importance in metabolism, the role of glycine N-acyltransferase, and factors that influence interindividual variation.

23650932

Neoplasms

Overexpression of lipid metabolism genes and PBX1 in the contralateral breasts of women with estrogen receptor-negative breast cancer.

28263391

Neoplasms

The expression and prognostic value of GLYATL1 and its potential role in hepatocellular carcinoma.

33457003

Porphyrias

The role of substrates for glycine acyltransferase, and the role of sulfanilamide and acetate in the reversal of chemically-induced porphyria in the rat.

4791042

Prostatic Neoplasms

Characterization of glycine-N-acyltransferase like 1 (GLYATL1) in prostate cancer.

31376196

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