2.3.1.129: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase

This is an abbreviated version!
For detailed information about acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.129

2.3.1.129

udp-glcnac

lipopolysaccharide

left-handed

acyl-acp

endotoxin

drug development

beta-helix

beta-helical

homotrimer

udp-3-o-r-3-hydroxymyristoyl-glcnac

raetz

medicine

Reaction

a (3R)-3-hydroxyacyl-[acyl-carrier protein]

a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine

Synonyms

acyltransferase, uridine diphosphoacetylglucosamine, LiLpxA, LpxA, type II ACP-dependent UDP-N-acetylglucosamine acyltransferase, type II acyl carrier protein-dependent UDP-N-acetylglucosamine acyltransferase, UDP-N-acetylglucosamine 3-O-acyltransferase, UDP-N-acetylglucosamine acyltransferase, uridine diphosphoacetylglucosamine acyltransferase

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.129 acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase

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Results	in table
19502	AA Sequence
5	Application
1	CAS Registry Number
23	Cloned(Commentary)
14	Crystallization (Commentary)
13	General Information
2	General Stability
17	IC50 Value
41	Inhibitors
3	Ki Value [mM]
9	KM Value [mM]
3	Localization
9	Metals/Ions
10	Molecular Weight [Da]
36	Natural Substrates/ Products (Substrates)
83	Organism
10	Pathway
236	PDB ID
13	pH Optimum
64	Protein Variants
6	Purification (Commentary)
4	Reaction
1	Reaction Type
65	Reference
1	Source Tissue
63	Specific Activity [micromol/min/mg]
2	Storage Stability
129	Substrates and Products (Substrate)
16	Subunits
48	Synonyms
1	Systematic Name
14	Temperature Optimum [°C]
4	Temperature Stability [°C]
3	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.3.1.129 - acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase

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(R)-3-hydroxydodecanoyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

[acyl-carrier protein] + UDP-3-N-(3-hydroxydodecanoyl)-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

Leptospira interrogans

first step in lipid A biosynthesis pathway, lipid A is an unusual variant in this species containing 2,3-diamino-2,3-dideoxy-D-glucopyranose units

659349

(R)-3-hydroxytetradecanoyl-[acyl-carrier protein] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

[acyl-carrier protein] + UDP-3-N-(3-hydroxytetradecanoyl)-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose

2 entries

(R)-3-hydroxytetradecanoyl-[acyl-carrier protein] + UDP-N-acetyl-alpha-D-glucosamine

[acyl-carrier protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetyl-alpha-D-glucosamine

23 entries

an (R)-3-hydroxytetradecanoyl-[acyl-carrier protein] + UDP-N-acetyl-alpha-D-glucosamine

an [acyl-carrier protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetyl-alpha-D-glucosamine

3 entries

additional information

3 entries