2.3.1.129: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase

This is an abbreviated version!
For detailed information about acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.129

2.3.1.129

udp-glcnac

lipopolysaccharide

left-handed

acyl-acp

endotoxin

drug development

beta-helix

beta-helical

homotrimer

udp-3-o-r-3-hydroxymyristoyl-glcnac

raetz

medicine

Reaction

a (3R)-3-hydroxyacyl-[acyl-carrier protein]

a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine

Synonyms

acyltransferase, uridine diphosphoacetylglucosamine, LiLpxA, LpxA, type II ACP-dependent UDP-N-acetylglucosamine acyltransferase, type II acyl carrier protein-dependent UDP-N-acetylglucosamine acyltransferase, UDP-N-acetylglucosamine 3-O-acyltransferase, UDP-N-acetylglucosamine acyltransferase, uridine diphosphoacetylglucosamine acyltransferase

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.129 acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase

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Results	in table
19502	AA Sequence
5	Application
1	CAS Registry Number
23	Cloned(Commentary)
14	Crystallization (Commentary)
13	General Information
2	General Stability
17	IC50 Value
41	Inhibitors
3	Ki Value [mM]
9	KM Value [mM]
3	Localization
9	Metals/Ions
10	Molecular Weight [Da]
36	Natural Substrates/ Products (Substrates)
83	Organism
10	Pathway
236	PDB ID
13	pH Optimum
64	Protein Variants
6	Purification (Commentary)
4	Reaction
1	Reaction Type
65	Reference
1	Source Tissue
63	Specific Activity [micromol/min/mg]
2	Storage Stability
129	Substrates and Products (Substrate)
16	Subunits
48	Synonyms
1	Systematic Name
14	Temperature Optimum [°C]
4	Temperature Stability [°C]
3	Turnover Number [1/s]

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Cloned on EC 2.3.1.129 - acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase

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3 entries

expressed in Escherchia coli as a His-tagged fusion protein

Escherichia coli

P0A722

706784

expressed in Escherichia coli

Leptospira interrogans

Q8EZA6

702322

expression in Corynebacterium glutamicum

Escherichia coli

486260

expression in Escherichia coli

5 entries

gene lpxA, cloning from strain strain MG1655, subcloning in strain XL-1 Blue, expression in Escherichia coli strain BL21-AI/pET24a

Escherichia coli

718571

gene lpxA, DNA and amino acid sequence determination and analysis, expression in Escherichia coli strain BL21(DE3)

Acidithiobacillus ferrooxidans

Q6QHI7

659349

gene lpxA, DNA and amino acid sequence determination, subcloning in Escherichia coli, wild-type and mutant strains expression analysis

Moraxella catarrhalis

Q3BDJ0

673981

gene lpxA, excluding the region encoding the predicted signal peptide (residues 2-32), expression of the plant enzyme in Escherichia coli strain C41(DE3). Functional expression of AtlpxA in and complementation of the constructed lpxA Escherichia coli knockout mutant strains

Arabidopsis thaliana

Q9SU91

718930

gene lpxA, expression in Escherichia coli strain BL21(DE3)

Leptospira interrogans

659349

gene lpxA, expression in strain BL21(DE3)

Escherichia coli

659349

gene lpxA, five AtLpxC orthologues located in a 68-kb region on chromosome one, DNA and amino acid sequence determination and analysis, sequence comparison

Arabidopsis thaliana

Q9SU91

720913

overexpression in Escherichia coli

4 entries

recombinant expresssion

Escherichia coli

718462