2.3.1.125: 1-alkyl-2-acetylglycerol O-acyltransferase

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For detailed information about 1-alkyl-2-acetylglycerol O-acyltransferase, go to the full flat file.

Reaction

Synonyms

1-hexadecyl-2-acetylglycerol acyltransferase, acyltransferase, 1-hexadecyl-2-acetylglycerol

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.125 1-alkyl-2-acetylglycerol O-acyltransferase

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1	Activating Compound
1	CAS Registry Number
7	Inhibitors
1	Ki Value [mM]
1	KM Value [mM]
1	Localization
1	Metals/Ions
1	Natural Substrates/ Products (Substrates)
1	Organism
1	Pathway
1	pH Optimum
1	Reaction
1	Reaction Type
1	Reference
1	Source Tissue
2	Substrates and Products (Substrate)
2	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
3	Temperature Stability [°C]

Inhibitors

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Inhibitors on EC 2.3.1.125 - 1-alkyl-2-acetylglycerol O-acyltransferase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

1-O-Hexadecyl-2-oleoyl-sn-glycerol

Homo sapiens

-

competitive inhibitor of 1-hexadecyl-2-acetyl-3-acyl-sn-glycerol synthesis

486246

1-oleoyl-2-acetyl-sn-glycerol

Homo sapiens

-

mixed-type inhibition

486246

Ca2+

Homo sapiens

-

6% inhibition at 2 mM

486246

Cu2+

Homo sapiens

-

96% inhibition at 2 mM

486246

dithiothreitol

Homo sapiens

-

-

486246

Mn2+

Homo sapiens

-

35% inhibition at 2 mM

486246

Zn2+

Homo sapiens

-

93% inhibition at 2 mM

486246