2.3.1.123: dolichol O-acyltransferase
This is an abbreviated version!
For detailed information about dolichol O-acyltransferase, go to the full flat file.
Reaction
Synonyms
acyl-CoA:dolichol acyltransferase, acyltransferase, dolichol
ECTree
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Substrates Products on EC 2.3.1.123 - dolichol O-acyltransferase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
acetyl-CoA + dolichol
CoA + dolichyl acetate
-
30% of activity compared to palmitoyl-CoA
-
-
?
arachidonoyl-CoA + dolichol
CoA + dolichyl arachidonate
-
30% of activity compared to palmitoyl-CoA
-
-
?
myristoyl-CoA + dolichol
CoA + dolichyl myristate
-
40% of activity compared to palmitoyl-CoA
-
-
?
oleoyl-CoA + dolichol
CoA + dolichyl oleate
-
40% of activity compared to palmitoyl-CoA
-
-
?
stearoyl-CoA + dolichol
CoA + dolichyl stearate
-
40% of activity compared to palmitoyl-CoA
-
-
?
additional information
?
-
-
alpha-saturated dolichols are acylated more rapidly than alpha-unsaturated analogues
-
-
?
additional information
?
-
-
esterfication may play a role in targeting the lipid from the endoplasmic reticulum to lysosomes
-
-
?
