2.3.1.122: trehalose O-mycolyltransferase

This is an abbreviated version!
For detailed information about trehalose O-mycolyltransferase, go to the full flat file.

Word Map on EC 2.3.1.122

2.3.1.122

tuberculosis

mycobacterium

bovis

esat-6

antigen-specific

ifn-gamma

bacille

ankara

prime-boost

mva85a

immunodominant

mycolylation

bcg-vaccinated

mycolic

tuberculin

booster

polyfunctional

aerosol

bcg-primed

calmette-guerin

elispot

drug development

th1-type

fibronectin-binding

bcg-induced

medicine

tuberculosis-infected

biotechnology

dimycolate

post-vaccination

ifn-gamma-producing

Reaction

2 alpha,alpha-trehalose 6-mycolate =

Synonyms

Ag85A, ag85C, alpha,alpha'-trehalose 6-monomycolate:alpha,alpha'-trehalose mycolyltransferase, antigen 85A, antigen 85C, cg0413, CMT1, corynomycoloyl transferase C, FbpA mycolyltransferase, mycoloyl transferase, mycolyl-transferase Ag85A, mycolyltransferase, mycolyltransferase, trehalose 6-monomycolate-trehalose, MytC

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.122 trehalose O-mycolyltransferase

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Results	in table
2530	AA Sequence
3	Application
1	CAS Registry Number
8	Cloned(Commentary)
1	Cofactor
5	Crystallization (Commentary)
9	General Information
3	General Stability
20	IC50 Value
40	Inhibitors
4	KM Value [mM]
4	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
27	Organism
2	Pathway
19	PDB ID
7	pH Optimum
1	pH Range
9	Protein Variants
7	Purification (Commentary)
6	Reaction
1	Reaction Type
24	Reference
3	Specific Activity [micromol/min/mg]
26	Substrates and Products (Substrate)
2	Subunits
38	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 2.3.1.122 - trehalose O-mycolyltransferase

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0.01

(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-methyl ethyl butylphosphonate

Mycobacterium avium

IC50: 0.010 mM

673449

0.041

(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-methyl ethyl tetradecylphosphonate

Mycobacterium avium

IC50: 0.0410 mM

673449

0.0013

(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl ethyl heptylphosphonate

Mycobacterium avium

IC50: 0.0013 mM

673449

0.0871

(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl ethyl nonylphosphonate

Mycobacterium avium

IC50: 0.0871 mM

673449

0.0043

1-(3-phenoxy)benzyl 1-octanesulfonate

Mycobacterium tuberculosis

P9WQN9

IC50: 0.0043 mM

675106

0.0507

2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-ethyl ethyl butylphosphonate

Mycobacterium avium

IC50: 0.0507 mM

673449

0.0257

2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-ethyl ethyl nonylphosphonate

Mycobacterium avium

IC50: 0.0257 mM

673449

0.102

3,4,5-trimethoxybenzylphosphonate

Mycobacterium avium

IC50: 0.102 mM

673449

0.002

ethyl 3-phenoxybenzyl butylphosphonate

2 entries

0.021

ethyl 3-phenoxybenzyl heptylphosphonate

Mycobacterium avium

IC50: 0.021 mM

673449

0.0426

ethyl 3-phenoxybenzyl hexylphosphonate

Mycobacterium avium

IC50: 0.0426 mM

673449

0.0148

ethyl 3-phenoxybenzyl nonylphosphonate

Mycobacterium avium

IC50: 0.0148 mM

673449

0.862

ethyl 3-phenoxybenzyl tetradecylphosphonate

Mycobacterium avium

IC50: 0.862 mM

673449

0.225

ethyl hydrogen 2-phenylethyl phosphonate

Mycobacterium avium

IC50: 0.225 mM

673449

0.11

ethyl hydrogen 4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)butylphosphonate

Mycobacterium avium

IC50: 0.110 mM

673449

0.431

ethyl hydrogen butylphosphonate

Mycobacterium avium

IC50: 0.431 mM

673449

0.0011

ethyl hydrogen heptylphosphonate

Mycobacterium avium

IC50: 0.0011 mM

673449

0.0036

ethyl hydrogen hexylphosphonate

Mycobacterium avium

IC50: 0.0036 mM

673449

0.471

ethyl hydrogen nonylphosphonate

Mycobacterium avium

IC50: 0.471 mM

673449