2.3.1.107: deacetylvindoline O-acetyltransferase

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For detailed information about deacetylvindoline O-acetyltransferase, go to the full flat file.

Reaction

Synonyms

17-O-deacetylvindoline O-acetyltransferase, 17-O-deacetylvindoline-17-O-acetyltransferase, acetyl-CoA-17-O-deacetylvindoline 17-O-acetyltransferase, acetyl-CoA: 4-O-deacetylvindoline 4-O-acetyltransferase, acetylcoenzyme A-deacetylvindoline 4-O-acetyltransferase, acetylcoenzyme A:deacetylvindoline 4-O-acetyltransferase, acetylcoenzyme A:deacetylvindoline O-acetyltransferase, acetyltransferase, deacetylvindoline, DAT, deacetyl vindoline 4-O-acetyl transferase, deacetylvindoline acetyl CoA acetyltransferase, deacetylvindoline acetyl-CoA acetyl transferase, deacetylvindoline acetyltransferase, deacetylvindoline-4-O-acetyltransferase

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.107 deacetylvindoline O-acetyltransferase

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Results	in table
3	Activating Compound
8	AA Sequence
3	Application
1	CAS Registry Number
7	Cloned(Commentary)
5	Cofactor
5	Expression
6	General Information
9	Inhibitors
1	Ki Value [mM]
8	KM Value [mM]
4	Localization
1	Metals/Ions
5	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
19	Organism
3	Pathway
2	pH Optimum
2	pH Range
2	Protein Variants
5	Purification (Commentary)
1	Reaction
1	Reaction Type
19	Reference
34	Source Tissue
15	Specific Activity [micromol/min/mg]
1	Storage Stability
18	Substrates and Products (Substrate)
3	Subunits
26	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Application

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Application on EC 2.3.1.107 - deacetylvindoline O-acetyltransferase

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APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

agriculture

Catharanthus roseus

-

treatment with cold plasma upregulates the expressions of deacetylvindoline O-acetyltransferase gene by an average of 7.8 times. Plasma priming induces activities of phenylalanine ammonia-lyase, catalase (about twofold) and peroxidase (31%). The plasma-treated seedlings contain higher concentrations of alkaloids

756520

drug development

Catharanthus roseus

Q9ZTK5

vincristine and vinblastine are secondary metabolites from Catharanthus roseus with very high pharmacological value that are used in treating cancer. However, these compounds are synthesised in Catharanthus roseus plants with very low content. The vincristine contents of four transgenic lines expressing the CrDAT gene are increased from 162.59% to 247.76% compared with the non-transgenic plants

765187

medicine

Catharanthus roseus

Q9ZTK5

production of therapeutically valuable terpenoid indole alkaloids

706200