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2.3.1.1: amino-acid N-acetyltransferase

This is an abbreviated version!
For detailed information about amino-acid N-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.1

Reaction

acetyl-CoA
+
L-glutamate
=
CoA
+
N-acetyl-L-glutamate

Synonyms

acetylglutamate synthase, acetylglutamate synthetase, acetylglutamic synthetase, acetyltransferase, amino acid, AGAS, amino acid acetyltransferase, ARG2, ArgA, ArgH(A), argJ, Cg3035, More, N-acetyl-glutamate synthase, N-acetyl-L-glutamate synthase, N-acetyl-L-glutamate synthase/kinase, N-acetyl-L-glutamate synthetase, N-acetylglutamate synthase, N-acetylglutamate synthase/kinase, N-acetylglutamate synthetase, NAGS, NAGS-K, NAGS/K, NAT, ngNAGS, PaNAGS, pitax, Rv2747, SINAGS1, XcNAGS

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.1 amino-acid N-acetyltransferase

Molecular Weight

Molecular Weight on EC 2.3.1.1 - amino-acid N-acetyltransferase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
160000
-
gel filtration, sucrose density gradient centrifugation
190000
-
gel filtration
202400
calculated from amino acid sequence
20978
21000
220100
gel filtration
263000
tetrameric structure in the presence and absence of L-arginine, gel fitlration and ultracentrifugation
277000
-
tetramer-octamer equilibrium that shifts towards tetramers upon binding of L-arginine, gel fitlration and ultracentrifugation
30000 - 300000
-
gel filtration, mixture of multiple forms
300000
gel filtration
330000
gel filtration
37200
37400
38800
catalytic N-acetyltransferase domain, calculated from amino acid sequence
40000
x * 40000, SDS-PAGE, x * 40322, calculated
40322
x * 40000, SDS-PAGE, x * 40322, calculated
51700
-
6 * 51700, SDS-PAGE, cross-linking studies with dimethylsuberimidate, in the maximally aggregated state the enzyme exists as a hexamer
52000
-
4 * 52000, catalytic domain, SDS-PAGE
52752
-
4 * 52752, catalytic domain, calculated from amino acid sequence
55000
-
4 * 55000, mature enzyme, SDS-PAGE
55498
-
4 * 55498, mature enzyme, calculated from amino acid sequence
57000
-
3 * 57000, SDS-PAGE
73000
-
x * 73000, deduced from nucleotide sequence of the mature enzyme
additional information
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