2.1.4.1: glycine amidinotransferase

This is an abbreviated version!
For detailed information about glycine amidinotransferase, go to the full flat file.

Word Map on EC 2.1.4.1

2.1.4.1

creatine

guanidinoacetate

homoarginine

slc6a8

harg

phosphocreatine

medicine

creatine-deficient

transamidination

Reaction

Synonyms

AGAT, arginine-glycine amidinotransferase, arginine-glycine transamidinase, arginine:glycine amidinotransferase, CyrA, EC 2.6.2.1, GAT, GATM, glycine amidinotransferase, glycine aminotransferase, glycine transamidinase, L-arginine:glycine amidinotransferase

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.4 Amidinotransferases

2.1.4.1 glycine amidinotransferase

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Results	in table
7	Activating Compound
1310	AA Sequence
9	Application
1	CAS Registry Number
14	Cloned(Commentary)
1	Crystallization (Commentary)
165	Disease/ Diagnostics
5	Expression
16	General Information
50	Inhibitors
3	Ki Value [mM]
39	KM Value [mM]
25	Localization
34	Molecular Weight [Da]
96	Natural Substrates/ Products (Substrates)
583	Organism
8	Pathway
11	PDB ID
16	pH Optimum
4	pH Range
1	pH Stability
2	pI Value
9	Protein Variants
12	Purification (Commentary)
3	Reaction
6	Reaction Type
81	Reference
187	Source Tissue
13	Specific Activity [micromol/min/mg]
2	Storage Stability
246	Substrates and Products (Substrate)
21	Subunits
41	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
2	Temperature Range [°C]
4	Temperature Stability [°C]
2	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 2.1.4.1 - glycine amidinotransferase

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2-thio-6-aminouracil

2 entries

2-thio-6-oxopurine

2 entries

2-Thiouracil

2 entries

2-thiouracil-5-carboxylic acid

2 entries

5,5'-dithiobis-2-nitrobenzoate

CO2

Creatine

Cu2+

dithiobiuret

glycine

inhibits in presence of low amounts of arginine

485966

guanidine hydrochloride

HCO3-

Hg2+

L-norvaline

L-ornithine

NH4+

NH4+-induced decrease in creatine and guanidinoacetate probably occurs through inhibition of AGAT enzymatic activity

Ni2+

ornithine

p-chloromercuribenzoate

thiolhistidine

Zn2+