2.1.3.7: 3-hydroxymethylcephem carbamoyltransferase
This is an abbreviated version!
For detailed information about 3-hydroxymethylcephem carbamoyltransferase, go to the full flat file.
Reaction
Synonyms
carbamoyltransferase, 3-hyroxymethylcephem
ECTree
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Substrates Products
Substrates Products on EC 2.1.3.7 - 3-hydroxymethylcephem carbamoyltransferase
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REACTION DIAGRAM
carbamoyl phosphate + 7-aminodeacetylcephalosporanic acid
7-beta-acylamino-3-carbamoyloxymethylcephem + phosphate
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-
-
-
?
carbamoyl phosphate + 7beta-acylamino-3-hydroxymethylcephem
7beta-acylamino-3-carbamoyloxymethylcephem + phosphate
-
-
-
-
?
carbamoyl phosphate + a 3-hydroxymethyl ceph-3-em-4-carboxylate
phosphate + a 3-carbamoyloxymethylcephem
carbamoyl phosphate + decarbamoylcefuroxime
carbamoylcefuroxime + phosphate
-
-
-
?
carbamoyl phosphate + [3-hydroxymethyl]deacetylcephalosporin C
7beta-(5-D-aminoadipamido)-3-carbamoyloxymethylceph-3-em-4-carboxylic acid + phosphate
-
ATP may be a substrate or an effector
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?
phosphate + a 3-carbamoyloxymethylcephem
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the cmcH gene - encoding 3-hydroxymethylcephem carbamoyltransferase - upstream region does not contain a functional promoter, suggesting that cmcH is transcribed as a part of a polycistronic mRNA
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-
?
carbamoyl phosphate + a 3-hydroxymethyl ceph-3-em-4-carboxylate
phosphate + a 3-carbamoyloxymethylcephem
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enzyme is involved in biosynthesis of cephamycin
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-
?
carbamoyl phosphate + a 3-hydroxymethyl ceph-3-em-4-carboxylate
phosphate + a 3-carbamoyloxymethylcephem
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catalyzes the synthesis of a wide range of carbamoyloxymethylcephems, e.g. cefuroxime
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?