Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.1.3.3: ornithine carbamoyltransferase

This is an abbreviated version!
For detailed information about ornithine carbamoyltransferase, go to the full flat file.

Word Map on EC 2.1.3.3

Reaction

Carbamoyl phosphate
+
L-ornithine
=
phosphate
 +
L-citrulline

Synonyms

anabolic ornithine carbamoyltransferase, anabolic ornithine transcarbamoylase, AOTC, arcB gene product, ArgF, ArgK, aTtOTCase, carbamoyltransferase, carbamoyltransferase, ornithine, carbamylphosphate-ornithine transcarbamylase, catabolic ornithine carbamoyltransferase, catabolic ornithine transcarbamylase, citrulline phosphorylase, cOTC, L-ornithine carbamoyltransferase, L-ornithine carbamyltransferase, L-ornithine transcarbamylase, Lmo0036, MB1684, Mtb OTC, OCT, ornithine carbamoyltransferase, ornithine carbamoytransferase, ornithine carbamyl transferase, ornithine carbamyltransferase, ornithine transcarbamoylase, ornithine transcarbamylase, ornithine transcarbamylase 3, OTC, otcase, ROTCase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.3 Carboxy- and carbamoyltransferases
                2.1.3.3 ornithine carbamoyltransferase

pH Optimum

pH Optimum on EC 2.1.3.3 - ornithine carbamoyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
10
-
anabolic reaction
5 - 6
-
catabolic reaction
6.5
-
at 55°C
6.7
-
in potassium phosphate buffer 5 mM ornithine, pH optimum shifts to more alkaline values with decreasing ornithine concentrations
7.1
-
ornithine synthesis
7.25
-
wild type
7.3
-
catabolic ornithine carbamoyltransferase
7.4
-
assay at
7.6
-
triethanolamine/acetate buffer
7.7
-
triethanolamine buffer, 85% of maximal activity at pH 8.5, 25% of maximal activity at pH 6.8
7.9
-
HEPES/NaOH buffer
8.4 - 8.8
-
-
8.5 - 9.5
-
phaseolotoxin sensitive isoform 1
8.6
-
at 0.025 mM ornithine
8.8
30% of maximal activity at pH 7.0