2.1.3.2: aspartate carbamoyltransferase

This is an abbreviated version!
For detailed information about aspartate carbamoyltransferase, go to the full flat file.

Reaction

Synonyms

(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase, ACT, aspartate carbamoyltransferase, aspartate carbamyltransferase, aspartate trans carbamoylase, aspartate transcarbamoylase, aspartate transcarbamylase, aspartic acid transcarbamoylase, aspartic carbamyltransferase, aspartic transcarbamylase, ATC, ATC domain of CAD, ATCase, CAD, carbamoylaspartotranskinase, carbamoyltransferase, aspartate, carbamylaspartotranskinase, L-aspartate transcarbamoylase, L-aspartate transcarbamylase, MJ1581, PYRB

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.3 Carboxy- and carbamoyltransferases

                2.1.3.2 aspartate carbamoyltransferase

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Results	in table
60	Activating Compound
42879	AA Sequence
1	CAS Registry Number
28	Cloned(Commentary)
4	Cofactor
41	Crystallization (Commentary)
125	Disease/ Diagnostics
33	General Information
13	General Stability
18	IC50 Value
253	Inhibitors
66	Ki Value [mM]
77	KM Value [mM]
4	Localization
5	Metals/Ions
61	Molecular Weight [Da]
113	Natural Substrates/ Products (Substrates)
162	Organism
8	Pathway
316	PDB ID
24	pH Optimum
2	pH Range
3	pH Stability
1	Posttranslational Modification
61	Protein Variants
46	Purification (Commentary)
38	Reaction
2	Reaction Type
161	Reference
3	Renatured (Commentary)
36	Source Tissue
40	Specific Activity [micromol/min/mg]
9	Storage Stability
224	Substrates and Products (Substrate)
49	Subunits
104	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
3	Temperature Range [°C]
29	Temperature Stability [°C]
8	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 2.1.3.2 - aspartate carbamoyltransferase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-10°C -20°C, many months, no loss of activity

Bacillus subtilis

-

485857

-20°C, 0.1-1 mg protein/ml, at least 2 years, no loss of activity 4°C, 0.1-1 mg/ml, at least 2 months, no loss of activity

Enterococcus faecalis

-

485858, 485860

-20°C, 2 mM carbamoyl phosphate, 1 mM 2-mercaptoethanol, at least a week, no loss of activity

Mycolicibacterium smegmatis

-

485866

-20°C, 35 days, loss of 50% activity

Mya arenaria

-

661512

-80°C, 35 days, stable

Mya arenaria

-

661512

0-4°C, 1-2 days

Vigna radiata var. radiata

-

485862

4°C, 50 mM Tris-HCl, pH 7.5, 25% glycerol, 3 mM sodium azide, indefinitely, no loss of activity

Triticum aestivum

-

485878

4°C, mercaptoethanol-imidazole buffer, several months

Escherichia coli

-

485835