Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.1.3.2: aspartate carbamoyltransferase

This is an abbreviated version!
For detailed information about aspartate carbamoyltransferase, go to the full flat file.

Word Map on EC 2.1.3.2

Reaction

Carbamoyl phosphate
+
L-aspartate
=
phosphate
 +
N-carbamoyl-L-aspartate

Synonyms

(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase, ACT, aspartate carbamoyltransferase, aspartate carbamyltransferase, aspartate trans carbamoylase, aspartate transcarbamoylase, aspartate transcarbamylase, aspartic acid transcarbamoylase, aspartic carbamyltransferase, aspartic transcarbamylase, ATC, ATC domain of CAD, ATCase, CAD, carbamoylaspartotranskinase, carbamoyltransferase, aspartate, carbamylaspartotranskinase, L-aspartate transcarbamoylase, L-aspartate transcarbamylase, MJ1581, PYRB

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.3 Carboxy- and carbamoyltransferases
                2.1.3.2 aspartate carbamoyltransferase

IC50 Value

IC50 Value on EC 2.1.3.2 - aspartate carbamoyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0022
1,4,6,7-tetrabromo-2,3-naphthalenediol
Plasmodium falciparum
at pH 8.0 and 45°C
0.0055
2,3-naphthalenediol
Plasmodium falciparum
at pH 8.0 and 45°C
0.185
2-amino-3-naphthol
Plasmodium falciparum
at pH 8.0 and 45°C
0.2
2-methylquinazolin-4(3H)-one
Mus musculus
-
-
0.016
2-naphthol
Plasmodium falciparum
at pH 8.0 and 45°C
0.15
2-phenyl-1,3-4(H)benzothiazin-4-thione
Mus musculus
-
-
0.35
3-amino-6,8-dibromo-2-methyl-4(3H)-quinazolinone
Mus musculus
-
-
0.18
3-amino-6,8-dibromo-2-phenyl-4-(3H)-quinazolinone
Mus musculus
-
-
0.005 - 0.0154
4-(3-methyl-2,4,6-trioxo-2,3,4,5,6,11-hexahydro-1H-indeno[2',1':5,6]pyrido[2,3-d]pyrimidin-5-yl)phenyl 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoate
0.031
4-tert-butylcatechol
Plasmodium falciparum
at pH 8.0 and 45°C
0.0018 - 0.0041
5-([6-[(2E)-2-([2-[(2,4-dichlorophenyl)methoxy]phenyl]methylidene)hydrazinyl][1,2,5]oxadiazolo[3,4-b]pyrazin-5-yl]amino)-1,3-dihydro-2H-benzimidazol-2-one
0.0146
6,7-dibromo-2,3-naphthalenediol
Plasmodium falciparum
at pH 8.0 and 45°C
0.0176
6-bromo-2-naphthol
Plasmodium falciparum
at pH 8.0 and 45°C
0.000055
N-(phosphonoacetyl)-L-aspartic acid
Escherichia coli
-
-
0.2 - 0.3
Thiobarbituric acid