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2.1.3.1: methylmalonyl-CoA carboxytransferase

This is an abbreviated version!
For detailed information about methylmalonyl-CoA carboxytransferase, go to the full flat file.

Word Map on EC 2.1.3.1

Reaction

(S)-methylmalonyl-CoA
+
pyruvate
=
propanoyl-CoA
+
oxaloacetate

Synonyms

5S subunit of transcarboxylase, carboxyltransferase subunit of acetyl-CoA carboxylase, carboxyltransferase, methylmalonyl coenzyme A, DtsR1, MCT, methyl malonyl CoA carboxyl transferase, methylmalonyl CoA carboxyltransferase, methylmalonyl CoA-oxalacetate transcarboxylase, methylmalonyl coenzyme A carboxyltransferase, methylmalonyl-CoA carboxyltransferase, methylmalonyl-CoA transcarboxylase, MMC, oxalacetic transcarboxylase, transcarboxylase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.3 Carboxy- and carbamoyltransferases
                2.1.3.1 methylmalonyl-CoA carboxytransferase

General Stability

General Stability on EC 2.1.3.1 - methylmalonyl-CoA carboxytransferase

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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
alkaline pH, low ionic strength, monovalent ions, low protein concentration and elevated temperatures favor dissociation to inactive 5S, 6S and 1.3S subunits
glycerol, 20% retards dissociation of 12S and 6S-biotinyl subunit
-
polyvalent anions stabilize
-