2.1.2.8: deoxycytidylate 5-hydroxymethyltransferase

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For detailed information about deoxycytidylate 5-hydroxymethyltransferase, go to the full flat file.

Reaction

Synonyms

d-cytidine 5'-monophosphate hydroxymethylase, DCH, dCMP Hmase, dCMP hydroxymethylase, deoxyCMP hydroxymethylase, deoxycytidylate hydroxymethylase, deoxycytidylate hydroxymethyltransferase, deoxycytidylic hydroxymethylase, hydroxymethyltransferase, deoxycytidylate

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.2 Hydroxymethyl-, formyl- and related transferases

                2.1.2.8 deoxycytidylate 5-hydroxymethyltransferase

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Results	in table
1	Activating Compound
39	AA Sequence
1	CAS Registry Number
14	Cloned(Commentary)
33	Cofactor
2	Crystallization (Commentary)
13	Inhibitors
8	Ki Value [mM]
2	KM Value [mM]
1	Localization
17	Molecular Weight [Da]
19	Natural Substrates/ Products (Substrates)
18	Organism
3	Pathway
9	PDB ID
1	pH Optimum
17	Protein Variants
11	Purification (Commentary)
7	Reaction
1	Reaction Type
18	Reference
7	Specific Activity [micromol/min/mg]
3	Storage Stability
37	Substrates and Products (Substrate)
8	Subunits
14	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Stability [°C]
5	Turnover Number [1/s]

Cloned

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Cloned on EC 2.1.2.8 - deoxycytidylate 5-hydroxymethyltransferase

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

cloning and overexpression of g42 in Escherichia coli K38

Tequatrovirus T4

-

485783

expressed in Escherichia coli BL21(DE3) cells

Tequatrovirus T4

P08773

757025

gene 42 encoding enzyme is sequenced and expressed in Escherichia coli

Tequatrovirus T4

P08773

485792

nucleotide sequence of dCMP hydroxymethylase gene encoding a protein of 246 amino acids

2 entries

nucleotide sequence of g42, the dCMP hydroxymethylase gene, encodes a protein of 246 amino acids

Tequatrovirus T4

-

485782, 485783

overexpression in Escherichia coli BL21

Tequatrovirus T4

-

485791

structural gene 42 encodes enzyme

Tequatrovirus T4

-

209854, 485786, 485788, 485789, 485790, 485791

nucleotide sequence of dCMP hydroxymethylase gene encoding a protein of 246 amino acids

Escherichia phage T2

-

485783

nucleotide sequence of dCMP hydroxymethylase gene encoding a protein of 246 amino acids

Enterobacteria phage T6

-

485783