2.1.2.2: phosphoribosylglycinamide formyltransferase 1

This is an abbreviated version!
For detailed information about phosphoribosylglycinamide formyltransferase 1, go to the full flat file.

Word Map on EC 2.1.2.2

2.1.2.2

purine

antifolate

thymidylate

dihydrofolate

pemetrexed

formylation

polyglutamation

folate-dependent

multitargeted

ccrf-cem

folylpolyglutamate

aminoimidazole

alimta

lometrexol

aicar

ddathf

mta

medicine

trifunctional

5,10-dideazatetrahydrofolic

6-substituted

5-aminoimidazole-4-carboxamide

pyrrolo2,3-dpyrimidine

aminoimidazolecarboxamide

folate-requiring

trimetrexate

phosphoribosylaminoimidazole

monoglutamate

raltitrexed

5-formyltetrahydrofolate

igrov1

diagnostics

formylglycinamide

antipurine

Reaction

N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide

Synonyms

2-amino-N-ribosylacetamide 5'-phosphate (glycinamide ribotide) transformylase, 2-amino-N-ribosylacetamide 5'-phosphate transformylase, 5'-phosphoribosylglycinamide transformylase, 5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase, ADE8, GAR formyltransferase, GAR synthetase, GAR TFase, GAR transformylase, GARFT, GARFTase, GART, GART synthetase, GARTfase, glycinamide ribonucleotide formyl transferase, glycinamide ribonucleotide formyltransferase, glycinamide ribonucleotide transformylase, glycinamide ribotide formyltransferase, N10-formyltetrahydrolate:2-amino-N-ribosylacetamide-5'-phosphate transformylase, phosphoribosylglycinamide formyltransferase, PurN, purN transformylase, trifunctional purine biosynthetic protein adenosine-3

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.2 Hydroxymethyl-, formyl- and related transferases

2.1.2.2 phosphoribosylglycinamide formyltransferase 1

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Results	in table
4	Activating Compound
37241	AA Sequence
27	Application
1	CAS Registry Number
31	Cloned(Commentary)
22	Cofactor
13	Crystallization (Commentary)
202	Disease/ Diagnostics
6	General Information
90	IC50 Value
201	Inhibitors
47	Ki Value [mM]
88	KM Value [mM]
2	Localization
4	Metals/Ions
53	Molecular Weight [Da]
94	Natural Substrates/ Products (Substrates)
304	Organism
10	Pathway
80	PDB ID
6	pH Optimum
3	pH Range
1	pH Stability
12	Protein Variants
39	Purification (Commentary)
1	Reaction
5	Reaction Type
127	Reference
76	Source Tissue
10	Specific Activity [micromol/min/mg]
1	Storage Stability
277	Substrates and Products (Substrate)
51	Subunits
72	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
23	Turnover Number [1/s]

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