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2.1.2.2: phosphoribosylglycinamide formyltransferase 1

This is an abbreviated version!
For detailed information about phosphoribosylglycinamide formyltransferase 1, go to the full flat file.

Word Map on EC 2.1.2.2

Reaction

10-formyltetrahydrofolate
+
N1-(5-phospho-D-ribosyl)glycinamide
=
tetrahydrofolate
 +
N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide

Synonyms

2-amino-N-ribosylacetamide 5'-phosphate (glycinamide ribotide) transformylase, 2-amino-N-ribosylacetamide 5'-phosphate transformylase, 5'-phosphoribosylglycinamide transformylase, 5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase, ADE8, GAR formyltransferase, GAR synthetase, GAR TFase, GAR transformylase, GARFT, GARFTase, GART, GART synthetase, GARTfase, glycinamide ribonucleotide formyl transferase, glycinamide ribonucleotide formyltransferase, glycinamide ribonucleotide transformylase, glycinamide ribotide formyltransferase, N10-formyltetrahydrolate:2-amino-N-ribosylacetamide-5'-phosphate transformylase, phosphoribosylglycinamide formyltransferase, PurN, purN transformylase, trifunctional purine biosynthetic protein adenosine-3

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.2 Hydroxymethyl-, formyl- and related transferases
                2.1.2.2 phosphoribosylglycinamide formyltransferase 1

KM Value

KM Value on EC 2.1.2.2 - phosphoribosylglycinamide formyltransferase 1

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0775 - 0.0848
(6R)-N10-formyltetrahydrofolate
0.000075 - 33
10-formyl-5,8-dideazafolate
0.019
5,8-Dideazafolate
-
-
0.00368
acetate
-
purT gene product
0.0774
ATP
-
purT gene product
0.0011 - 33
beta-glycinamide ribonucleotide
0.0036 - 0.0465
carbocyclic beta-glycinamide ribonucleotide
0.018
carbocyclic glycinamide ribonucleotide
-
-
0.319
formate
-
purT gene product
0.102
formyl-beta-glycinamide ribonucleotide
-
-
0.01 - 0.4
glycinamide ribonucleotide
0.052
glycinamide ribotide
-
-
0.00576
L-(+)-5,10-methenyltetrahydrofolate
-
-
0.0008 - 0.00676
L-(-)-10-formyltetrahydrofolate
0.21
N-formylglycinamide ribotide
-
-
0.0211 - 0.099
N10-formyl-5,8-dideazafolate
0.19
N10-formyl-5-deazafolate
-
-
0.15
N10-Formyl-8-deazafolate
-
-
0.0167 - 0.0365
N10-formyldideazafolate
0.6
N10-formylfolate
-
-
0.058
N5,N10-anhydroformyl tetrahydrofolate
-
-