2.1.2.11: 3-methyl-2-oxobutanoate hydroxymethyltransferase

This is an abbreviated version!
For detailed information about 3-methyl-2-oxobutanoate hydroxymethyltransferase, go to the full flat file.

Reaction

Synonyms

5,10-methylene tetrahydrofolate:alpha-ketoisovalerate hydroxymethyltransferase, alpha-ketoisovalerate hydroxymethyltransferase, dehydropantoate hydroxymethyltransferase, hydroxymethyltransferase, ketopantoate, ketopantoate hydroxymethyl transferase, ketopantoate hydroxymethyltransferase, KHMT, KPHMT, MOHMT, oxopantoate hydroxymethyltransferase, PanB

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.2 Hydroxymethyl-, formyl- and related transferases

                2.1.2.11 3-methyl-2-oxobutanoate hydroxymethyltransferase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
38557	AA Sequence
2	Application
1	CAS Registry Number
10	Cloned(Commentary)
30	Cofactor
2	Crystallization (Commentary)
10	General Information
2	General Stability
17	Inhibitors
22	KM Value [mM]
4	Localization
21	Metals/Ions
19	Molecular Weight [Da]
23	Natural Substrates/ Products (Substrates)
58	Organism
7	Pathway
45	PDB ID
7	pH Optimum
3	pH Range
4	pH Stability
1	Posttranslational Modification
6	Protein Variants
7	Purification (Commentary)
10	Reaction
1	Reaction Type
24	Reference
13	Specific Activity [micromol/min/mg]
1	Storage Stability
61	Substrates and Products (Substrate)
7	Subunits
26	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
2	Temperature Stability [°C]
3	Turnover Number [1/s]

KM Value

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

KM Value on EC 2.1.2.11 - 3-methyl-2-oxobutanoate hydroxymethyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to KM Value Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

2.9

2-oxobutyrate

Escherichia coli

-

-

485700

25

2-oxopentanoate

Escherichia coli

-

-

485700

0.24 - 1.1

3-methyl-2-oxobutanoate

2 entries

5.9

3-methyl-2-oxopentanoate

Escherichia coli

-

-

485700

0.82

5,10-methylenetetrahydrofolate

Mycobacterium tuberculosis

-

-

485710

5.9

formaldehyde

2 entries

0.15 - 0.16

ketopantoate

2 entries

0.18

tetrahydrofolate

2 entries

0.25

tetrahydropteroyldiglutamate

Escherichia coli

-

-

485700

0.29

tetrahydropteroylheptaglutamate

Escherichia coli

-

-

485700

0.17

tetrahydropteroylhexaglutamate

Escherichia coli

-

-

485700

0.33

tetrahydropteroylmonoglutamate

Escherichia coli

-

-

485700

0.1

Tetrahydropteroylpentaglutamate

Escherichia coli

-

-

485700

0.1

tetrahydropteroyltetraglutamate

Escherichia coli

-

-

485700

0.18

tetrahydropteroyltriglutamate

Escherichia coli

-

-

485700

additional information

additional information

2 entries

-

0.24

3-methyl-2-oxobutanoate

Mycobacterium tuberculosis

-

-

485710

1.1

3-methyl-2-oxobutanoate

Escherichia coli

-

-

485700, 485701

5.9

formaldehyde

Escherichia coli

-

-

485701

5.9

formaldehyde

Escherichia coli

-

methylenetetrahydrofolate: formaldehyde + tetrahydrofolate

485700

0.15

ketopantoate

Escherichia coli

-

-

485707

0.16

ketopantoate

Escherichia coli

-

-

485700

0.18

tetrahydrofolate

Escherichia coli

-

-

485701

0.18

tetrahydrofolate

Escherichia coli

-

forward and reverse reaction, methylenetetrahydrofolate: formaldehyde + tetrahydrofolate

485700

additional information

additional information

Mycobacterium tuberculosis

-

-

485710

-

additional information

additional information

Escherichia coli

-

low Km-values for its substrates

485699

-