2.1.1.B85: 7'-O-demethylcephaline methyltransferase
This is an abbreviated version!
For detailed information about 7'-O-demethylcephaline methyltransferase, go to the full flat file.
Reaction
Synonyms
CiOMT1, IpeOMT2
ECTree
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Substrates Products
Substrates Products on EC 2.1.1.B85 - 7'-O-demethylcephaline methyltransferase
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REACTION DIAGRAM
S-adenosyl-L-methionine + cephaeline
S-adenosyl-L-homocysteine + emetine
the enzyme is involved in emetine biosynthesis. IpeOMT2 does not catalyze the 6'-O-methylation of cephaeline
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S-adenosyl-L-homocysteine + cephaeline
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S-adenosyl-L-methionine + 7'-O-demethylcephaeline
S-adenosyl-L-homocysteine + cephaeline
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IpeOMT2 does not catalyze the 6'-O-methylation of cephaeline. IpeOMT2 shows broad substrate specificity towards the intermediates in emetine biosynthesis. The regional substrate specificity for 7'-O-demethylcephaeline (the penultimate step of emetine biosynthesis) is restricted to 7'-O-methylation
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additional information
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IpeOMT2 does not catalyze the 6'-O-methylation of cephaeline. IpeOMT2 shows broad substrate specificity towards the intermediates in emetine biosynthesis. The regional substrate specificity for 7'-O-demethylcephaeline (the penultimate step of emetine biosynthesis) is restricted to 7'-O-methylation
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additional information
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CiOMT1 also catalyzes the formation of emetine from cephaeline
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additional information
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CiOMT1 also catalyzes the formation of emetine from cephaeline
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additional information
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substrate specificity of CiOMT2, overview
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additional information
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substrate specificity of CiOMT2, overview
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