2.1.1.B43: tRNA (cytosine49-C5)-methyltransferase
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For detailed information about tRNA (cytosine49-C5)-methyltransferase, go to the full flat file.
Reaction
Synonyms
PAB1946
ECTree
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Activating Compound
Activating Compound on EC 2.1.1.B43 - tRNA (cytosine49-C5)-methyltransferase
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archaease
in vitro, the purified recombinant methyltransferase catalyzes 5-methylcytosine formation at several cytosines within tRNAs with preference for C49. The specificity of the methyltransferase is increased by the archease. In solution, the archease exists as a monomer, trimer, and hexamer. Only the oligomeric states bind the methyltransferase and prevent its aggregation, in addition to hindering dimerization of the methyltransferase-tRNA complex
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