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2.1.1.9: thiol S-methyltransferase

This is an abbreviated version!
For detailed information about thiol S-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.9

Reaction

S-adenosyl-L-methionine
+
a thiol
=
S-adenosyl-L-homocysteine
 +
a methyl thioether

Synonyms

AtHOL1, CrSMT1, HMT, HMT/HTMT, HTMT, Met S-methyltransferase, methionine S-methyltransferase, methyltransferase, thiol, MMT, OsHOL1, OsHOL2, PpSABATH1, S-adenosyl-L-methionine-dependent halide/thiol methyltransferase, S-adenosylmethionine-dependent halide/thiol methyltransferase, S-methyltransferase, S-methyltransferase 1, SABATH methyltransferase, SAM-dependent halide methyltransferase, thiol methyltransferase, thiol S-methyltransferase, TMT

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.9 thiol S-methyltransferase

Reference

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Reference on EC 2.1.1.9 - thiol S-methyltransferase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kim, Y.H.; Joo, I.
Arylamine N-methyltransferase and thiol methyltransferase activities in cholestatic rat liver induced by common bile duct ligation
Exp. Mol. Med.
33
23-28
2001
Rattus norvegicus
Manually annotated by BRENDA team
Borchardt, R.T.; Cheng, C.F.
Purification and characterization of rat liver microsomal thiol methyltransferase
Biochim. Biophys. Acta
522
340-353
1978
Rattus norvegicus
Manually annotated by BRENDA team
Weisiger, R.A.; Jakoby, W.B.
Thiol S-methyltransferase from rat liver
Arch. Biochem. Biophys.
196
631-637
1979
Rattus norvegicus
Manually annotated by BRENDA team
Bremer, J.; Greenberg, D.M.
Enzymic methylation of foreign sulfhydryl compounds
Biochim. Biophys. Acta
46
217-224
1961
Bos taurus, Cavia porcellus, Gallus gallus, Oryctolagus cuniculus, Ovis aries, Mus musculus, Rattus norvegicus
-
Manually annotated by BRENDA team
Weisiger, R.A.; Jakoby, W.B.
Thiol S-methyltransferase
Methods Enzymol.
77
257-262
1981
Rattus norvegicus
Manually annotated by BRENDA team
Holloway, C.J.; Tegtmeier, F.; Brunner, G.; Trautschold, I.
Gas chromatographic method for the quantitative assay of alkane thiol S-methyltransferase
J. Chromatogr.
202
423-429
1980
Oryctolagus cuniculus
Manually annotated by BRENDA team
Glauser, T.A.; Kerremans, A.L.; Weinshilboum, R.M.
Human hepatic microsomal thiol methyltransferase. Assay conditions, biochemical properties, and correlation studies
Drug Metab. Dispos.
20
247-255
1992
Homo sapiens
Manually annotated by BRENDA team
Otterness, D.M.; Keith, R.A.; Kerremans, A.L.; Weinshilboum, R.M.
Mouse liver thiol methyltransferase. Assay conditions, biochemical properties, and strain variation
Drug Metab. Dispos.
14
680-688
1986
Mus musculus
Manually annotated by BRENDA team
Drotar, A.M.; Fall, R.
Methylation of xenobiotic thiols by Euglena gracilis: Characterization of a cytoplasmic thiol methyltransferase
Plant Cell Physiol.
26
847-854
1985
Euglena gracilis
-
Manually annotated by BRENDA team
Weisiger, R.A.; Pinkus, L.M.; Jakoby, W.B.
Thiol S-methyltransferase: Suggested role in detoxication of intestinal hydrogen sulfide
Biochem. Pharmacol.
29
2885-2887
1980
Rattus norvegicus
Manually annotated by BRENDA team
Weinshilboum, R.M.; Sladek, S.; Klumpp, S.
Human erythrocyte thiol methyltransferase: Radiochemical microassay and biochemical properties
Clin. Chim. Acta
97
59-71
1979
Homo sapiens
Manually annotated by BRENDA team
Attieh, J.; Sparace, S.A.; Saini, H.S.
Purification and properties of multiple isoforms of a novel thiol methyltransferase involved in the production of volatile sulfur compounds from Brassica oleracea
Arch. Biochem. Biophys.
380
257-266
2000
Brassica oleracea
Manually annotated by BRENDA team
Roediger, W.E.; Babidge, W.J.
Thiol methyltransferase activity in inflammatory bowel disease
Gut
47
206-210
2000
Homo sapiens
Manually annotated by BRENDA team
Attieh, J.; Djiana, R.; Koonjul, P.; Etienne, C.; Sparace, S.A.; Saini, H.S.
Cloning and functional expression of two plant thiol methyltransferases: a new class of enzymes involved in the biosynthesis of sulfur volatiles
Plant Mol. Biol.
50
511-521
2002
Brassica oleracea (Q93V78), Brassica oleracea (Q93XC4)
Manually annotated by BRENDA team
Kocsis, M.G.; Ranocha, P.; Gage, D.A.; Simon, E.S.; Rhodes, D.; Peel, G.J.; Mellema, S.; Saito, K.; Awazuhara, M.; Li, C.; Meeley, R.B.; Tarczynski, M.C.; Wagner, C.; Hanson, A.D.
Insertional inactivation of the methionine S-methyltransferase gene eliminates the S-methylmethionine cycle and increases the methylation ratio
Plant Physiol.
131
1808-1815
2003
Arabidopsis thaliana, Zea mays
Manually annotated by BRENDA team
Coiner, H.; Schroeder, G.; Wehinger, E.; Liu, C.J.; Noel, J.P.; Schwab, W.; Schroeder, J.
Methylation of sulfhydryl groups: a new function for a family of small molecule plant O-methyltransferases
Plant J.
46
193-205
2006
Catharanthus roseus
Manually annotated by BRENDA team
Ohsawa, N.; Tsujita, M.; Morikawa, S.; Itoh, N.
Purification and characterization of a monohalomethane-producing enzyme S-adenosyl-L-methionine: halide ion methyltransferase from a marine microalga, Pavlova pinguis
Biosci. Biotechnol. Biochem.
65
2397-2404
2001
Pavlova pinguis
Manually annotated by BRENDA team
Itoh, N.; Toda, H.; Matsuda, M.; Negishi, T.; Taniguchi, T.; Ohsawa, N.
Involvement of S-adenosylmethionine-dependent halide/thiol methyltransferase (HTMT) in methyl halide emissions from agricultural plants: isolation and characterization of an HTMT-coding gene from Raphanus sativus (daikon radish)
BMC Plant Biol.
9
116
2009
Raphanus sativus (C6L2E7), Raphanus sativus
Manually annotated by BRENDA team
Nagatoshi Y, Nakamura T.
Arabidopsis HARMLESS TO OZONE LAYER protein methylates a glucosinolate breakdown product and functions in resistance to Pseudomonas syringae pv. maculicola
J. Biol. Chem.
284
19301-19309
2009
Arabidopsis thaliana (Q0WP12)
Manually annotated by BRENDA team
Saini, H.S.; Attieh, J.M.; Hanson, A.D.
Biosynthesis of halomethanes and methanethiol by higher plants via a novel methyltransferase reaction
Plant Cell Environ.
18
1027-1033
1995
Brassica oleracea
-
Manually annotated by BRENDA team
Schmidberger, J.; James, A.; Edwards, R.; Naismith, J.; OHagan, D.
Halomethane biosynthesis: Structure of a SAM-dependent halide methyltransferase from arabidopsis thaliana
Angew. Chem. Int. Ed. Engl.
49
3646-3648
2010
Arabidopsis thaliana (Q0WP12), Arabidopsis thaliana
Manually annotated by BRENDA team
Toda, H.; Itoh, N.
Isolation and characterization of a gene encoding a S-adenosyl-L-methionine-dependent halide/thiol methyltransferase (HTMT) from the marine diatom Phaeodactylum tricornutum: Biogenic mechanism of CH3I emissions in oceans
Phytochemistry
72
337-343
2011
Phaeodactylum tricornutum (B7FWR0), Phaeodactylum tricornutum, Phaeodactylum tricornutum CCAP 1055/1 (B7FWR0)
Manually annotated by BRENDA team
Takekawa, Y.; Nakamura, T.
Rice OsHOL1 and OsHOL2 proteins have S-adenosyl-L-methionine-dependent methyltransferase activities toward iodide ions
Plant Biotechnol.
29
103-108
2012
Oryza sativa
-
Manually annotated by BRENDA team
Obach, R.S.; Prakash, C.; Kamel, A.M.
Reduction and methylation of ziprasidone by glutathione, aldehyde oxidase, and thiol S-methyltransferase in humans: an in vitro study
Xenobiotica
42
1049-1057
2012
Homo sapiens
Manually annotated by BRENDA team
Zhao, N.; Ferrer, J.L.; Moon, H.S.; Kapteyn, J.; Zhuang, X.; Hasebe, M.; Neal Stewart, C.; Gang, D.R.; Chen, F.
A SABATH Methyltransferase from the moss Physcomitrella patens catalyzes S-methylation of thiols and has a role in detoxification
Phytochemistry
81
31-41
2012
Physcomitrium patens
Manually annotated by BRENDA team
Liu, C.; Chen, Z.; Zhong, K.; Li, L.; Zhu, W.; Chen, X.; Zhong, D.
Human liver cytochrome P450 enzymes and microsomal thiol methyltransferase are involved in the stereoselective formation and methylation of the pharmacologically active metabolite of clopidogrel
Drug Metab. Dispos.
43
1632-1641
2015
Homo sapiens
Manually annotated by BRENDA team
Maw, H.H.; Zeng, X.; Campbell, S.; Taub, M.E.; Teitelbaum, A.M.
N-Methylation of BI 187004 by thiol S-methyltransferase
Drug Metab. Dispos.
46
770-778
2018
Homo sapiens
Manually annotated by BRENDA team