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2.1.1.89: tetrahydrocolumbamine 2-O-methyltransferase

This is an abbreviated version!
For detailed information about tetrahydrocolumbamine 2-O-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
5,8,13,13a-tetrahydrocolumbamine
=
S-adenosyl-L-homocysteine
+
tetrahydropalmatine

Synonyms

CoOMT, methyltransferase, tetrahydrocolumbamine, tetrahydrocolumbamine methyltransferase, tetrahydrocolumbamine O-methyltransferase, tetrahydrocolumbamine OMT

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.89 tetrahydrocolumbamine 2-O-methyltransferase

Natural Substrates Products

Natural Substrates Products on EC 2.1.1.89 - tetrahydrocolumbamine 2-O-methyltransferase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + (R,S)-5,8,13,13a-tetrahydrocolumbamine
S-adenosyl-L-homocysteine + (R,S)-tetrahydropalmatine
show the reaction diagram
-
-
-
ir
S-adenosyl-L-methionine + tetrahydrocolumbamine
S-adenosyl-L-homocysteine + tetrahydropalmatine
show the reaction diagram
-
enzyme is involved in the biosynthesis of berberine alkaloids
-
?