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2.1.1.85: protein-histidine N-methyltransferase

This is an abbreviated version!
For detailed information about protein-histidine N-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
protein L-histidine
=
S-adenosyl-L-homocysteine
+
protein Ntau-methyl-L-histidine

Synonyms

actin His73 nmethyltransferase, actin histidine methyltransferase, actin histidine-N3 methyltransferase, actin-specific histidine methyltransferase, actin-specific histidine N-methyltransferase, actin-specific methyltransferase, methyltransferase, protein (histidine), protein (actin) histidine MTase, protein methylase IV, S-adenosyl methionine:protein-histidine N-methyltransferase, SET domain protein 3, setd3

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.85 protein-histidine N-methyltransferase

Reference

Reference on EC 2.1.1.85 - protein-histidine N-methyltransferase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Raghavan, M.; Lindberg, U.; Schutt, C.
The use of alternative substrates in the characterization of actin-methylating and carnosine-methylating enzymes
Eur. J. Biochem.
210
311-318
1992
Oryctolagus cuniculus
Manually annotated by BRENDA team
Vijayasarathy, C.; Rao, B.S.N.
Partial purification and characterisation of S-adenosylmethionine:protein-histidine N-methyltransferase from rabbit skeletal muscle
Biochim. Biophys. Acta
923
156-165
1987
Oryctolagus cuniculus
Manually annotated by BRENDA team
Kwiatkowski, S.; Seliga, A.K.; Vertommen, D.; Terreri, M.; Ishikawa, T.; Grabowska, I.; Tiebe, M.; Teleman, A.A.; Jagielski, A.K.; Veiga-da-Cunha, M.; Drozak, J.
SETD3 protein is the actin-specific histidine N-methyltransferase
eLife
7
e37921
2018
Rattus norvegicus
Manually annotated by BRENDA team
Guo, Q.; Liao, S.; Kwiatkowski, S.; Tomaka, W.; Yu, H.; Wu, G.; Tu, X.; Min, J.; Drozak, J.; Xu, C.
Structural insights into SETD3-mediated histidine methylation on beta-actin
eLife
8
e43676
2019
Homo sapiens (Q86TU7)
Manually annotated by BRENDA team
Dai, S.; Horton, J.R.; Woodcock, C.B.; Wilkinson, A.W.; Zhang, X.; Gozani, O.; Cheng, X.
Structural basis for the target specificity of actin histidine methyltransferase SETD3
Nat. Commun.
10
3541
2019
Homo sapiens (Q86TU7)
Manually annotated by BRENDA team
Wilkinson, A.W.; Diep, J.; Dai, S.; Liu, S.; Ooi, Y.S.; Song, D.; Li, T.M.; Horton, J.R.; Zhang, X.; Liu, C.; Trivedi, D.V.; Ruppel, K.M.; Vilches-Moure, J.G.; Casey, K.M.; Mak, J.; Cowan, T.; Elias, J.E.; Nagamine, C.M.; Spudich, J.A.; Cheng, X.; Carette, J.E.; Gozani, O.
SETD3 is an actin histidine methyltransferase that prevents primary dystocia
Nature
565
372-376
2019
Mus musculus, Homo sapiens (Q86TU7), Homo sapiens
Manually annotated by BRENDA team