2.1.1.79: cyclopropane-fatty-acyl-phospholipid synthase

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For detailed information about cyclopropane-fatty-acyl-phospholipid synthase, go to the full flat file.

Reaction

Synonyms

C17:cyclopropane synthase, Cfa, CFA synthase, cfaB, CFAS, CPS, CPS1, CPS2, CPS3, cyclopropane fatty acid synthase, cyclopropane fatty acid synthetase, cyclopropane fatty acyl synthase, cyclopropane synthase, cyclopropane-fatty-acyl-phospholipid synthase, HP0416, SfCPA-FAS, synthetase, cyclopropane fatty acid, unsaturated-phospholipid methyltransferase

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.79 cyclopropane-fatty-acyl-phospholipid synthase

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Results	in table
4	Activating Compound
6587	AA Sequence
1	CAS Registry Number
15	Cloned(Commentary)
1	Crystallization (Commentary)
7	Expression
20	General Information
3	General Stability
11	IC50 Value
49	Inhibitors
2	kcat/KM [mM/s]
19	Ki Value [mM]
25	KM Value [mM]
11	Localization
5	Molecular Weight [Da]
21	Natural Substrates/ Products (Substrates)
272	Organism
5	Pathway
18	PDB ID
5	pH Optimum
1	pH Range
15	Protein Variants
13	Purification (Commentary)
2	Reaction
1	Reaction Type
49	Reference
12	Source Tissue
5	Specific Activity [micromol/min/mg]
3	Storage Stability
64	Substrates and Products (Substrate)
15	Subunits
74	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Stability [°C]
14	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.1.1.79 - cyclopropane-fatty-acyl-phospholipid synthase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

19 entries

additional information

?

-

2 entries

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Escherichia coli

P0A9H7

-

733434, 756262

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Escherichia coli

-

-

756262

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Escherichia coli

-

increased level of cyclopropane fatty acid synthase activity as bacterial cultures enter stationary phase is transient, activity quickly declines to the basal level, the loss of activity is due to proteolytic degradation dependent on expression of the heat shock regulon

485632

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Escherichia coli

-

methylation of unsaturated fatty acid moieties of phospholipids in the phospholipid bilayer

485631

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Escherichia coli

-

the enzyme acts on sn-2 of phospholipids

734968

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Helicobacter pylori

-

-

757104

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Helicobacter pylori 26695

-

-

757104

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Lacticaseibacillus casei

-

-

734414

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Lacticaseibacillus casei ATCC 334

-

-

734414

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Lactiplantibacillus plantarum

-

S-adenosylmethionine levels in conjugation with cyclopropane fatty acid synthase activities regulates cyclopropane fatty acid synthesis in Lactobacillus plantarum

485630

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Lactobacillus acidophilus

Q5FJM0

-

757117

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Lactobacillus acidophilus NCFM

Q5FJM0

-

757117

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Lactococcus lactis

-

the cfa locus is an essential component of the acid stress response of Lactococcus lactis MG1363

679889

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Lactococcus lactis MG1363

-

the cfa locus is an essential component of the acid stress response of Lactococcus lactis MG1363

679889

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Leishmania infantum

-

-

735077

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Leishmania mexicana

-

-

757012

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Leishmania mexicana M379

-

-

757012

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Oenococcus oeni

-

-

733222

-

-

?

S-adenosyl-L-methionine + phospholipid olefinic fatty acid

S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

Salmonella enterica

-

increase in expression of CFA synthase at early stationary phase is due to the alternative sigma factor RpoS

659895

-

-

?

additional information

?

-

Pseudomonas putida

-

growth conditions that result in an increase in the relative amount of C17:cyclopropane fatty acid yield better survival after lyophilization

677669

-

-

?

additional information

?

-

Pseudomonas putida KT 2240

-

growth conditions that result in an increase in the relative amount of C17:cyclopropane fatty acid yield better survival after lyophilization

677669

-

-

?