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2.1.1.79: cyclopropane-fatty-acyl-phospholipid synthase

This is an abbreviated version!
For detailed information about cyclopropane-fatty-acyl-phospholipid synthase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
phospholipid olefinic fatty acid
=
S-adenosyl-L-homocysteine
+
phospholipid cyclopropane fatty acid

Synonyms

C17:cyclopropane synthase, Cfa, CFA synthase, cfaB, CFAS, CPS, CPS1, CPS2, CPS3, cyclopropane fatty acid synthase, cyclopropane fatty acid synthetase, cyclopropane fatty acyl synthase, cyclopropane synthase, cyclopropane-fatty-acyl-phospholipid synthase, HP0416, SfCPA-FAS, synthetase, cyclopropane fatty acid, unsaturated-phospholipid methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.79 cyclopropane-fatty-acyl-phospholipid synthase

IC50 Value

IC50 Value on EC 2.1.1.79 - cyclopropane-fatty-acyl-phospholipid synthase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.007
(12aS,12bS)-7-fluoro-2,3,5,12,12a,12b-hexahydro-1H,4H-11-oxa-3a,9b-diazabenzo[a]naphtho[2,1,8-cde]azulene
Escherichia coli
-
-
0.01
(1R,7aR)-hexahydro-1H-pyrrolizin-1-ylmethyl 4-hydroxy-3,5-dimethoxybenzoate
Escherichia coli
-
-
0.004
1,2,5-trimethyl-2,3,4,6-tetrahydro-1H-pyrido[4,3-b]carbazole
Escherichia coli
-
-
0.005
2,5,11-trimethyl-2,3,4,6-tetrahydro-1H-pyrido[4,3-b]carbazole
Escherichia coli
-
-
0.009
3beta,5alpha-17a-aza-D-homoandrostan-3-ol
Escherichia coli
-
-
0.01
5'-S-[2-(decylamino)ethyl]-5'-thioadenosine
Escherichia coli
-
-
0.001
9-methoxy-1,2,5-trimethyl-2,3,4,6-tetrahydro-1H-pyrido[4,3-b]carbazole
Escherichia coli
-
-
0.004 - 0.06381
dioctylamine
0.009 - 0.01
sinefungin