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2.1.1.76: quercetin 3-O-methyltransferase

This is an abbreviated version!
For detailed information about quercetin 3-O-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.76

Reaction

S-adenosyl-L-methionine
+
3,5,7,3',4'-pentahydroxyflavone
=
S-adenosyl-L-homocysteine
+
3-methoxy-5,7,3',4'-tetrahydroxyflavone

Synonyms

3-OMT, CdFOMT5, flavonoid 3-methyltransferase, flavonoid-O-methyltransferase, flavonol 3-O-methyltransferase, FOMT5, Mg2+-independent O-methyltransferase, MOMT3, More, quercetin 3-O-methyltransferase 1, S-adenosyl-L-methionine:quercetin 3-O-methyltransferase, trimethylfavonol 3'/5'-OMT

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.76 quercetin 3-O-methyltransferase

Substrates Products

Substrates Products on EC 2.1.1.76 - quercetin 3-O-methyltransferase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
4 S-adenosyl-L-methionine + quercetin
4 S-adenosyl-L-homocysteine + 3,3',5,7-tetramethoxyquercetin
show the reaction diagram
whole-cell biocatalysis using CdFOMT5 expressed in Escherichia coli cells is performed using quercetin as a substrate, and 3,3',5,7-tetramethylated quercetin is obtained as the final product
-
-
?
S-adenosyl-L-methionine + 3',5'-O-dimethylmyricetin
S-adenosyl-L-homocysteine + 3,3',5'-O-trimethylmyricetin
show the reaction diagram
-
18% activity compared to myricetin
-
-
?
S-adenosyl-L-methionine + 3'-O-methylmyricetin
S-adenosyl-L-homocysteine + 3,3'-O-dimethylmyricetin
show the reaction diagram
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone
S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone
show the reaction diagram
S-adenosyl-L-methionine + 3-O-methylquercetin
S-adenosyl-L-homocysteine + ?
show the reaction diagram
-
3% activity compared to myricetin
-
-
?
S-adenosyl-L-methionine + 4'-O-methylkaempferol
S-adenosyl-L-homocysteine + 3,4'-O-dimethylkaempferol
show the reaction diagram
-
11% activity compared to myricetin
-
-
?
S-adenosyl-L-methionine + 7-methylquercetin
?
show the reaction diagram
-
i.e. rhamnetin, 30% of the activity with quercetin
-
-
?
S-adenosyl-L-methionine + 7-O-methylmyricetin
S-adenosyl-L-homocysteine + 3,7-O-dimethylquercetin
show the reaction diagram
-
104% activity compared to myricetin
-
-
?
S-adenosyl-L-methionine + galangin
S-adenosyl-L-homocysteine + ?
show the reaction diagram
-
60% of the activity with quercetin
-
-
?
S-adenosyl-L-methionine + isorhamnetin
S-adenosyl-L-homocysteine + ?
show the reaction diagram
-
88% of the activity with quercetin
-
-
?
S-adenosyl-L-methionine + kaempferol
S-adenosyl-L-homocysteine + 3-O-methyl-kaempferol
show the reaction diagram
-
93% of the activity with quercetin
-
-
?
S-adenosyl-L-methionine + kaempferol
S-adenosyl-L-homocysteine + 3-O-methylkaempferol
show the reaction diagram
-
53% activity compared to myricetin
-
-
?
S-adenosyl-L-methionine + myricetin
S-adenosyl-L-homocysteine + 3-O-methyl-myricetin
show the reaction diagram
-
46% of the activity with quercetin
-
-
?
S-adenosyl-L-methionine + myricetin
S-adenosyl-L-homocysteine + 3-O-methylmyricetin
show the reaction diagram
-
100% activity
-
-
?
S-adenosyl-L-methionine + myricetin
S-adenosyl-L-homocysteine + ?
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + quercetin
S-adenosyl-L-homocysteine + 3'-methoxyquercetin
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + quercetin
S-adenosyl-L-homocysteine + 3-methoxyquercetin
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + quercetin
S-adenosyl-L-homocysteine + 3-O-methyl-quercetin
show the reaction diagram
-
-
-
-
?
S-adenosyl-L-methionine + quercetin
S-adenosyl-L-homocysteine + 3-O-methylquercetin
show the reaction diagram
-
121% activity compared to myricetin
-
-
?
S-adenosyl-L-methionine + quercetin
S-adenosyl-L-homocysteine + 5-methoxyquercetin
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + quercetin
S-adenosyl-L-homocysteine + 7-methoxyquercetin
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + tamarixetin
S-adenosyl-L-homocysteine + ?
show the reaction diagram
-
85% of the activity with quercetin
-
-
?
additional information
?
-