2.1.1.7: nicotinate N-methyltransferase

This is an abbreviated version!
For detailed information about nicotinate N-methyltransferase, go to the full flat file.

Reaction

Synonyms

At3g53140, furanocoumarin 8-methyltransferase, furanocoumarin 8-O-methyltransferase, methyltransferase, nicotinate, NANMT, nicotinate methyltransferase, nicotinic acid methyltransferase, NNMT, S-adenosyl-L-methionine:nicotinic acid-N-methyltransferase, T4D2.70, trigonelline synthase

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.7 nicotinate N-methyltransferase

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Results	in table
7	AA Sequence
1	CAS Registry Number
1	General Information
4	General Stability
15	Inhibitors
1	kcat/KM [mM/s]
8	KM Value [mM]
1	Metals/Ions
3	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
7	Organism
1	Oxidation Stability
2	Pathway
1	PDB ID
5	pH Optimum
3	pH Range
2	Purification (Commentary)
1	Reaction
1	Reaction Type
7	Reference
8	Source Tissue
5	Specific Activity [micromol/min/mg]
4	Storage Stability
13	Substrates and Products (Substrate)
1	Subunits
11	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 2.1.1.7 - nicotinate N-methyltransferase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

benzoic acid

Lemna aequinoctialis

-

-

441221

heavy metal ions

Lemna aequinoctialis

-

-

441221

-

Hg2+

2 entries

Isonicotinic acid

Lemna aequinoctialis

-

-

441221

Mg2+

Glycine max

-

slight

441222

p-hydroxymercuribenzoate

Glycine max

-

-

441222

parahydroxymercuric benzoate

Glycine max

-

at 0.1 mM, reversible by 10 mM DTT

658243

Picolinic acid

Lemna aequinoctialis

-

-

441221

Pyrazinamide

Lemna aequinoctialis

-

-

441221

S-adenosyl-L-homocysteine

Glycine max

-

-

441222

salicylic acid

Lemna aequinoctialis

-

-

441221

SH-blocking reagents

Glycine max

-

-

441222

-

Trigonelline

Lemna aequinoctialis

-

i.e. N-methylnicotinic acid

441221

additional information

Vigna radiata var. radiata

-

nicotinic acid and nicotinamide inhibit the growth of roots

659608

-

Hg2+

Glycine max

-

-

441222

Hg2+

Glycine max

-

at 1 mM, reversible by 10 mM DTT

658243