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2.1.1.67: thiopurine S-methyltransferase

This is an abbreviated version!
For detailed information about thiopurine S-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.67

Reaction

S-adenosyl-L-methionine
+
a thiopurine
=
S-adenosyl-L-homocysteine
+
a thiopurine S-methylether

Synonyms

6-thiopurine S-methyltransferase, 6-thiopurine transmethylase, mercaptopurine methyltransferase, thiopurine methyl transferase, thiopurine methyltransferase, thiopurine S-methyltransferase, thiopurine-S-methyl-transferase, TMPT, TPMT

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.67 thiopurine S-methyltransferase

Temperature Stability

Temperature Stability on EC 2.1.1.67 - thiopurine S-methyltransferase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
45 - 56
46.4
melting temperature of the wild type enzyme without ligand
46.8
melting temperature of the wild type enzyme in complex with S-adenosyl-L-methionine
55
-
the melting temperature of the wild type enzyme is at 55°C