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2.1.1.6: catechol O-methyltransferase

This is an abbreviated version!
For detailed information about catechol O-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.6

Reaction

S-adenosyl-L-methionine
+
a catechol
=
S-adenosyl-L-homocysteine
 +
a guaiacol

Synonyms

catechol methyltransferase, catechol-O-methyl transferase, catechol-O-methyl transferase, membrane bound, catechol-O-methyl transferase, soluble, catechol-O-methyltransferase, catechol-O-transferase, catecholamine O-methyltransferase, COMT, COMT I, COMT II, COMT-mb, COMT-s, COMT1, COMT2, CTOMT1, L-COMT, MB-COMT, methyltransferase, catechol, S-COMT, SCOMT

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.6 catechol O-methyltransferase

Storage Stability

Storage Stability on EC 2.1.1.6 - catechol O-methyltransferase

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STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-10°C, 3 months, stable
-
-20°C, 100 mM potassium phosphate, pH 8.0, 1 mM EDTA, 1 mM 2-mercaptoethanol, 5 mM dithiothreitol, 40% v/v glycerol, 1 mg/ml bovine serum albumin, stable for 4 months
-
-20°C, or -60°C, 50 mM Tris-HCl, pH 7.5, 20 mM 2-mercaptoethanol, 20% v/v glycerol, 60-80% of activity retained after 6 months
-
-4°C, stable for several weeks
-
-5°C, 20% v/v glycerol, stable for 6 months
-