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2.1.1.57: methyltransferase cap1

This is an abbreviated version!
For detailed information about methyltransferase cap1, go to the full flat file.

Word Map on EC 2.1.1.57

Reaction

S-adenosyl-L-methionine
+
a 5'-(N7-methyl 5'-triphosphoguanosine)-(ribonucleotide)-[mRNA]
=
S-adenosyl-L-homocysteine
+
a 5'-(N7-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleotide)-[mRNA]

Synonyms

(nucleoside-2'-O-)-methyltransferase, (nucleoside-2'O)-methyltransferase, 2'-O methyltransferase, 2'-O MTase, 2'-O-methyltransferase, 2'-O-MTase, 2'O methyltransferase, 2'O-MTase, 2'OMTases, cap-specific 2'-O-methyltransferase, cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, cap1 2-O'-ribose methyltransferase, CMTr1, EC 2.1.1.58, FtsJ methyltransferase domain-containing 2, FTSJD2, ISG95, KIAA0082, L protein domain VI, large polymerase protein domain VI, messenger ribonucleate nucleoside 2'-methyltransferase, messenger RNA (nucleoside-2'-)-methyltransferase, methyltransferase, messenger ribonucleate nucleoside 2'-, mRNA (nucleoside-2'-O)-methyltransferase, mRNA 5' cap-specific (nucleoside-2'-O)-methyltransferase, mRNA cap (nucleoside-2'-O)-methyltransferase, mRNA cap methyltransferase, mRNA cap-specific 2'-O-methyltransferase, MT57, Mtr1, nonstructural protein 16, nonstructural protein 16 methyltransferase, nonstructural protein 5 methyltransferase, NS5, NS5 MTase, NS5MTase, nsp10/16 complex, nsp10/nsp16 complex, nsp16, nsp16 protein, nsp16/nsp10 protein complex, ribose 2'-O methyltransferase, RNA (nucleoside-2'O)-methyltransferase, RNA cap 2'-O-methyltransferase, RNA cap 2'-O-MTase, RNA cap 2'O-MTase, RNA cap1 methyltransferase, RNA capping enzyme domain in protein A, S-adenosyl-L-methionine-dependent mRNA cap MTase, TbMT48, TbMT57, VP39, VP4

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.57 methyltransferase cap1

KM Value

KM Value on EC 2.1.1.57 - methyltransferase cap1

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.000394
7Me-GpppA-C5
-
in 40 mM Tris-HCl, pH 7.5, at 30°C
0.000005
brome mosaic virus RNA
-
-
-
0.0000014
G(5')pppA-poly(A)
-
-
0.0000016
m7G(5')pppA-poly(A)
-
-
1.8
m7G(5')pppG-RNA
-
apparent value, in glycine buffer (pH 10.0), at 22°C
-
0.00016 - 0.00023
RNA chain length 2-6 nt
-
-
-
0.000005 - 0.000015
RNA chain length 20-50 nt
-
-
-
0.0006 - 0.19
S-adenosyl-L-methionine
additional information
additional information
-
-
-