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2.1.1.56: mRNA (guanine-N7)-methyltransferase

This is an abbreviated version!
For detailed information about mRNA (guanine-N7)-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.56

Reaction

S-adenosyl-L-methionine
+
a 5'-(5'-triphosphoguanosine)-[mRNA]
=
S-adenosyl-L-homocysteine
+
a 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA]

Synonyms

(guanine-N7)-methyltransferase, Abd1, alphavirus capping enzyme, cap methyltransferase, cap N7-MTase, cap N7MTase, cap-methyltransferase, DENV methyltransferase, DENV-4 NS5, Ecm1, guanine-7-methyltransferase, guanine-N-7 methyltransferase, guanine-N7 methyltransferase, guanosine-7-methyltransferase, messenger ribonucleate guanine 7-methyltransferase, messenger RNA guanine 7-methyltransferase, methyltransferase domain of Sudan ebolavirus L protein, methyltransferase, messenger ribonucleate guanine 7-, mRNA cap (guanine N-7) methyltransferase, mRNA cap (guanine N-7) MTase, mRNA cap (guanine-N7) methyltransferase, mRNA cap methyltransferase, mRNA guanosine cap by RNA guanine-7-methyltransferase, MTase+CTD, N-7-MTase, N7 methyltransferase, N7 MTase, N7-methyltransferase, N7-MTase, non-structural protein 1, nonstructural protein 14, nonstructural protein 5 methyltransferase, NS5, NS5MTase, nsp 14, nsP1 methyltransferase, nsP1 MTase, nsp14, RNA (guanine-N7) methyltransferase, RNA cap (guanine N-7) methyltransferase, RNA guanine-7 methyltransferase, RNA guanine-7-methyltransferase, RNA guanine-methyltransferase, RNA guanine-N7 methyltransferase, RNA N7-MTase, RNMT, TbCgm1, TbCmt1

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.56 mRNA (guanine-N7)-methyltransferase

Substrates Products

Substrates Products on EC 2.1.1.56 - mRNA (guanine-N7)-methyltransferase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA]
S-adenosyl-L-homocysteine + a 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA]
show the reaction diagram
S-adenosyl-L-methionine + dGTP
S-adenosyl-L-homocysteine + m7dGTP
show the reaction diagram
S-adenosyl-L-methionine + G(5')pppA
S-adenosyl-L-homocysteine + m7G(5')pppA
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + G(5')pppG
S-adenosyl-L-homocysteine + m7G(5')pppG
show the reaction diagram
and dGTP, best substrates
-
-
?
S-adenosyl-L-methionine + G(5')pppN
S-adenosyl-L-homocysteine + m7G(5')pppG
show the reaction diagram
S-adenosyl-L-methionine + G(5')pppR-RNA
S-adenosyl-L-homocysteine + m7G(5')pppR-RNA
show the reaction diagram
S-adenosyl-L-methionine + GDP
S-adenosyl-L-homocysteine + m7GDP
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + Gppp-RNA
S-adenosyl-L-homocysteine + m7Gppp-RNA
show the reaction diagram
-
-
-
-
?
S-adenosyl-L-methionine + GpppA
S-adenosyl-L-homocysteine + m7GpppA
show the reaction diagram
S-adenosyl-L-methionine + GpppA-RNA
S-adenosyl-L-homocysteine + m7GpppA-RNA
show the reaction diagram
-
-
-
-
?
S-adenosyl-L-methionine + GpppAC3
S-adenosyl-L-homocysteine + m7GpppAC3
show the reaction diagram
-
is efficiently methylated at the guanine-N7 position
-
-
?
S-adenosyl-L-methionine + GpppAC4
S-adenosyl-L-homocysteine + 7mGpppAC4
show the reaction diagram
S-adenosyl-L-methionine + GpppG
S-adenosyl-L-homocysteine + m7GpppG
show the reaction diagram
S-adenosyl-L-methionine + GpppGAU-[RNA]
?
show the reaction diagram
-
strong activity
-
-
?
S-adenosyl-L-methionine + GTP
S-adenosyl-L-homocysteine + m7GTP
show the reaction diagram
S-adenosyl-L-methionine + guanylimidodiphosphate
?
show the reaction diagram
-
-
-
-
?
S-adenosyl-L-methionine + guanylylimidodiphosphate
?
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + m7G(5')pppG
S-adenosyl-L-homocysteine + ?
show the reaction diagram
-
-
-
?
S-adenosyl-L-methionine + mGpppGAU-[RNA]
?
show the reaction diagram
-
strong activity
-
-
?
S-adenosyl-L-methionine + mGpppGmAmU-[RNA]
?
show the reaction diagram
-
strong activity
-
-
?
S-adenosyl-L-methionine + mGpppGmAU-[RNA]
?
show the reaction diagram
-
strong activity
-
-
?
S-adenosyl-L-methionine + pp(A)n
?
show the reaction diagram
-
-
-
-
?
additional information
?
-