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2.1.1.54: deoxycytidylate C-methyltransferase

This is an abbreviated version!
For detailed information about deoxycytidylate C-methyltransferase, go to the full flat file.

Reaction

5,10-methylenetetrahydrofolate
+
dCMP
=
dihydrofolate
+
deoxy-5-methylcytidylate

Synonyms

dCMP methyltransferase, deoxycytidylate methyltransferase, methyltransferase, deoxycytidylate

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.54 deoxycytidylate C-methyltransferase

Metals Ions

Metals Ions on EC 2.1.1.54 - deoxycytidylate C-methyltransferase

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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Ca2+
-
25 mM, slight stimulation
Cu2+
-
below 1 mM, stimulation
K+
-
150 mM, stimulation
Mn2+
-
has a similar effect in stimulation but not as strong as Mg2+
Zn2+
-
below 1 mM, stimulation
additional information
-
among the buffers tested, 6-morpholinoethane sulfonate/Mg2+ is the best