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BRENDA support

2.1.1.5: betaine-homocysteine S-methyltransferase

This is an abbreviated version!
For detailed information about betaine-homocysteine S-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.5

Reaction

betaine
+
L-homocysteine
=
dimethylglycine
+
L-methionine

Synonyms

betaine homocysteine methyltransferase, betaine homocysteine methyltransferase-1, betaine homocysteine S-methyltransferase, betaine-homocysteine methyltransferase, betaine-homocysteine S-methyltransferase, betaine-homocysteine S-methyltransferase 2, betaine-homocysteine S-methyltransferase-2, betaine-homocysteine transmethylase, betaine:homocysteine methyltransferase, betaine:homocysteine S-methyltransferase, BHMT, BHMT-1, BHMT-2, BHMT1, BHMT2, methyltransferase, betaine-homocysteine

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.5 betaine-homocysteine S-methyltransferase

Source Tissue

Source Tissue on EC 2.1.1.5 - betaine-homocysteine S-methyltransferase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
BHMT expression is observed in the amygdala of basal ganglia and the cerebral cortex where BHMT levels are clearly elevated during torpor
Manually annotated by BRENDA team
-
-
Manually annotated by BRENDA team
BHMT expression is observed in the amygdala of basal ganglia and the cerebral cortex where BHMT levels are clearly elevated during torpor
Manually annotated by BRENDA team
-
low BHMT activity is detected in the G30 fetus, and slightly increased levels of activity are observed in the liver from G45 and G90 fetuses
Manually annotated by BRENDA team
hyperosmolarity (405 mosmol/l) suppresses Bhmt mRNA expression whereas hypoosmotic (205 mosmol/l) conditions induce Bhmt mRNA expression. Like hyperosmotic NaCl, hyperosmotic raffinose but not hyperosmotic urea suppresses Bhmt mRNA expression. Osmosensitivity of Bhmt mRNA expression is impaired by inhibitors of tyrosine kinases and cyclic nucleotide-dependent kinases
Manually annotated by BRENDA team
-
-
Manually annotated by BRENDA team
additional information