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2.1.1.49: amine N-methyltransferase

This is an abbreviated version!
For detailed information about amine N-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.49

Reaction

S-adenosyl-L-methionine
+
an amine
=
S-adenosyl-L-homocysteine
 +
a methylated amine

Synonyms

aromatic alkylamine-N-methyltransferase, arylamine N-methyltransferase, EC 2.1.1.81, methyltransferase, tryptamine, nicotine N-methyltransferase, tryptamine methyltransferase, tryptamine N-methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.49 amine N-methyltransferase

Specific Activity

Specific Activity on EC 2.1.1.49 - amine N-methyltransferase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.00000038
-
beta-phenylethylamine + S-adenosyl-L-methionine
0.00000118
-
tryptamine + S-adenosyl-L-methionine
0.0000012
-
N-methyltransferase A, (-)-(S)-isosalsoline
0.0000021
-
N-methyltransferase A, (-)-(S)-salsolidine
0.0000033
-
N-methyltransferase A, (+)-(R)-isosalsoline
0.000065
-
beta-phenylethylamine + 5-methyltetrahydrofolate
0.000068
-
N-methyltransferase A, aniline
0.000198
-
tryptamine + 5-methyltetrahydrofolate
0.00022
-
N-methyltransferase B, desmethylimipramine
0.00026
-
N-methyltransferase A, desmethylimipramine
0.00044
-
N-methyltransferase A, tryptamine
0.00127
-
N-methyltransferase B, aniline
0.0031
-
N-methyltransferase B, tryptamine
additional information
-
specific activities of serum, control and cholestatic liver in cytosolic, mitochondrial and microsomal preparations for 0.5, 1, 2, 3, 7, 14, 28 and 42 days after common bile duct ligation, activities of mitochondrial and microsomal enzyme in cholestatic liver and of serum enzyme increase after common bile duct ligation, Vmax-values