2.1.1.43: histone-lysine N-methyltransferase

This is an abbreviated version, for detailed information about histone-lysine N-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
histone L-lysine
=
S-adenosyl-L-homocysteine
+
histone N6-methyl-L-lysine

Synonyms

aKMT, Arabidopsis homolog of trithorax-1, ASH1, ASH1 HOMOLOG 2, Ash1L, Ash2L, ASHH1/SDG26, ASHH2, ATX1, chromatin histone H3-lysine 4 methyltransferase, CLF, COMPASS, COMPASS histone methyltransferase, dG9a, Dim-5, Dim-5 histone lysine methyltransferase, Dim-5 histone-3 lysine-9 methyltransferase, Dot1, DOT1B, DOT1L, Dpy-30, dSet1, Early Flowering in Short Days protein, EFS, EHMT2, ESET, Eu-HMTase1, EZH2, G9a, G9a histone methyltransferase, G9a lysine 9 histone H3 methyltransferase, G9a-like protein lysine methyltransferase, G9a/G9a-like protein lysine dimethyltransferase complex, G9A/KMT1C, GLP, grappa, H3-K4 HMT, H3K36 HMT, H3K36 methyltransferase, H3K4 HMT, H3K4 HMTase, H3K4 methyltransferase, H3K4 trimethyltransferase, H3K4MT, H3K9 histone methyltransferase, H3K9 histone methyltransferases, H3K9 HMT, H3K9 methyltransferase, H3K9-specific histone methyltransferases, H3K9-specific methyltransferase, H3K9-specific SET domain methyltransferase, H4K20 protein lysine methyltransferase, histone 3 lysine 4 methyltransferase, histone H1-specific S-adenosylmethionine:protein-lysine N-methyltransferase, histone H1.4K26 methyltransferase, histone H3 lysine 27 methyltransferase, histone H3 lysine 36 methyltransferase, histone H3 lysine 36 specific HMTase, histone H3 lysine 4 methyltransferase, histone H3 lysine 4 methyltransferase activity, histone H3 lysine 4 trimethyltransferase, histone H3 lysine 9 methyltransferase, histone H3 lysine methyltransferase G9a, histone H3 lysine-79 methyltransferase, histone H3 methyltransferase, histone H3-lysine-4 methyltransferase, histone H3K36 methyltransferase, histone H3K4 methyltransferase, histone H3K4 methyltransferase complex, histone H3K79 methyltransferase, histone H3K9 methyltransferase, histone H3K9 trimethylase, histone H4 lysine20 di- and trimethyltransferase, histone H4-K20 trimethyltransferase,, histone lysine (K) methyltransferase, histone lysine methyltransferase, histone lysine methyltransferase G9a, histone lysine methyltransferase SET7/9, histone lysine methyltransferases, histone methyltransferase, histone methyltransferase complex, histone methyltransferase G9a, HKMT, HKMTase, HMT, Hmt4-20/Suv4-20, HMTase, Hst1, huntingtin interacting protein B, hybrid sterility protein 1, HYPB, interleukin-5 response element II binding protein, Jarid1a, JumonjiC and ARID domain-containing histone lysine demethylase 1a, KMT, KMT2D, KMT5a, KMT7, Lid, lysine methyltransferase G9a, mDot1a, methyltransferase, protein (lysine), mixed lineage leukemia protein, MLL, MLL1, MLL3, MLL3/MLL4, MLL4, MMSET, murine disruptor of telomeric silencing alternative splice variant a, NSD1, NSD2, nuclear receptor SET domain 2, nuclear receptor-binding SET domain-protein 2, PA1, PKMT, Polycomb repressive complex 2, Pr-Set7, PRC2, PRDM8, Prdm9, protein (lysine) methyltransferase, protein lysine methyltransferase, protein lysine methyltransferases, protein methylase 3, protein methylase III, protein methyltransferase II, protein-lysine N-methyltransferase, Rad9, RbBP5, RE-IIBP, SDG724, SDG8, SET and MYND domain containing protein 3, SET and MYND domain-containing protein 2, SET domain containing protein 2, SET domain group 26, SET domain group protein 724, SET domain histone lysine methyltransferase, SET- and MYND-containing protein 2, SET-domain group protein 8, SET-domain protein lysine methyltransferase, SET1, set1 histone H3-Lys4 methyltransferase complex, SET1C, Set1p, SET2, SET3, SET7, SET7/9, SET7/9/Suv39h, SET8, SET8/PR-SET7, Set9, Set9 methyltransferase, Setd1A, Setd1B, SETD2, setd3, SetD7, SETD8, SETDB1, SETDB1/ESET, SiRe_1449, Smyd2, Smyd3, SU (VAR)3-9, SU(VAR)3-9, SUV39H1, Suv39H1/2, SUV420H2, SUVR4, TX1, vSET, Whsc1, WHSC1/MMSET isoform RE-IIBP, Wolf-Hirschhorn Syndrome candidate 1

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.43 histone-lysine N-methyltransferase