2.1.1.325: juvenile hormone-III synthase
This is an abbreviated version!
For detailed information about juvenile hormone-III synthase, go to the full flat file.
Word Map on EC 2.1.1.325
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2.1.1.325
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crustacean
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metamorphosis
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corpora
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allata
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ecdysteroids
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eyestalk
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pupation
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methoprene
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methoprene-tolerant
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portunus
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allatostatins
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nymphal
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trituberculatus
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spook
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bisepoxide
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cyp15a1
- 2.1.1.325
-
crustacean
-
metamorphosis
-
corpora
- allata
- ecdysteroids
- eyestalk
-
pupation
- methoprene
-
methoprene-tolerant
-
portunus
-
allatostatins
-
nymphal
- trituberculatus
-
spook
- bisepoxide
- cyp15a1
Reaction
Synonyms
FA-o-methyl transferase, FAMeT, FAMeT 1, FAMeT 2, FAOMeT, farnesoic acid methyltransferase, farnesoic acid O-methyl transferase, farnesoic acid O-methyltransferase, fmtD, JH acid methyltransferase, JHAMT, juvenile hormone acid methyl transferase, juvenile hormone acid methyltransferase, juvenile hormone acid O-methyltransferase, juvenile hormone acid-methyltransferase, MT3
ECTree
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General Information
General Information on EC 2.1.1.325 - juvenile hormone-III synthase
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malfunction
metabolism
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the enzyme has little if any effect on sesquiterpenoid biosynthesis
physiological function
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inhibition of enzyme transcription leads to inhibition of egg maturation and larval development
malfunction
dietary introduction of dsJHAMT1 and dsJHAMT2 successfully knock down the target gene, lower juvenile hormone titre in the haemolymph and reduce the transcript of Krüppel homologue 1 gene. Ingestion of dsJHAMT cause larval death and weight loss, shorten larval developmental period and impaire pupation. The JHAMT-fed pupae exhibit lower adult emergence rates. The resulting adults weighed an average of 50 mg less than the control group, and the females did not deposit eggs
malfunction
RNAi-triggered knock down of the enzyme (JHAMT) produces an extremely high reduction of synthesis of the juvenile hormone, concomitant with a decrease of fat body vitellogenin expression and basal follicle length
enzyme overexpression results in a pharate adult lethal phenotype suggesting that the temporal regulation of the enzyme is critical for Drosophila development
physiological function
the enzyme has a measurable role on the fertility
physiological function
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the enzyme is actively involved within larval development, metamorphosis and adult reproduction of Holcocerus hippophaecolus
physiological function
the enzyme is essential for juvenile hormone biosynthesis and for the maintenance of larval status
physiological function
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the enzyme is important for the regulation of eyestalk neuropeptides
physiological function
the enzyme is involved in physiological processes in addition to gametogenesis, oocyte maturation and development and metamorphosis. The enzyme modulates the reproduction and growth of crustaceans by interacting with the eyestalk neuropeptides as a consequence of its presence in the neurosecretory cells of the X-organ-sinus gland
physiological function
the enzyme is involved in regulation of the growth, reproduction and molting processes
physiological function
the enzyme plays an important role in the ovary development
physiological function
nutrition and its signaling through the insulin receptor and TOR pathways are essential for activating enzyme (JHAMT) expression, which suggests that this enzyme can be a checkpoint for the regulation of juvenile hormone production in relation to nutritional status
physiological function
R4ZEC6
the virus carries a gene encoding juvenile hormone acid methyltransferase, a key regulatory enzyme in insect metamorphosis