Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.1.1.325: juvenile hormone-III synthase

This is an abbreviated version!
For detailed information about juvenile hormone-III synthase, go to the full flat file.

Word Map on EC 2.1.1.325

Reaction

S-adenosyl-L-methionine
+
(2E,6E)-farnesoate
=
S-adenosyl-L-homocysteine
 +
methyl (2E,6E)-farnesoate

Synonyms

FA-o-methyl transferase, FAMeT, FAMeT 1, FAMeT 2, FAOMeT, farnesoic acid methyltransferase, farnesoic acid O-methyl transferase, farnesoic acid O-methyltransferase, fmtD, JH acid methyltransferase, JHAMT, juvenile hormone acid methyl transferase, juvenile hormone acid methyltransferase, juvenile hormone acid O-methyltransferase, juvenile hormone acid-methyltransferase, MT3

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.325 juvenile hormone-III synthase

Expression

Expression on EC 2.1.1.325 - juvenile hormone-III synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
enzyme activity is increases about 18fold 14 days after eyestalk ablation
-
enzyme expression significantly increases in the late-vitellogenic stage and mature stage of ovarian development
-
enzyme transcription is suppressed during metamorphosis
-
in females, the enzyme expression levels are significantly downregulated in eyestalk during ovarian development
in females, the enzyme expression levels are significantly up-regulated in thoracic ganglion during ovarian development, while in males expression levels increase in both thoracic ganglion and eyestalk during testicular development stages
in ovarian development, the mRNA level of the enzyme remains low in stage I and II, then increases considerably to a maximum in stage III, and declines slightly in stage IV
in the presence of S-benzyl-O-ethyl phosphoramidothiolate, homogenates of 0-day corpora allata show high levels of enzyme activity
-
mRNA expression is upregulated 6 h after Vibrio anguillarum challenge treatment in hemocytes and 12 h after Vibrio anguillarum challenge treatment in hepatopancreas
mRNA levels are reduced in starved females and in females in which nutritional signaling is reduced by knocking down insulin receptor and target of rapamycin
the enzyme is expressed specifically in the corpora allata throughout the third and fourth instar
the enzyme is undetectable in the pupal stage and during subsequent adult development, but increases again in adults by day 7
the enzyme's mRNA level gradually declines during larval development, and the lowest amount of expression is observed in the pupal stage, while it increases to a higher level during adult stages
-
the genes Tkv and Mad upregulate transcription and activity of the enzyme
transcript levels are high in early 4th instar larvae, undetectable in early and 1-day-old pupae, and rapidly increase 44-46 h after pupation to relatively high levels at adult eclosion (approximately 48-50 h after pupation)
-
transcript levels of the enzyme are not up-regulated by 20-hydroxyecdysone
-
treatment with mandibular organ-inhibiting hormone leads to a significant decline in enzyme activity and mRNA levels after 5h
-