Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.1.1.320: type II protein arginine methyltransferase

This is an abbreviated version!
For detailed information about type II protein arginine methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.320

Reaction

2 S-adenosyl-L-methionine +

[protein]-L-arginine
= 2 S-adenosyl-L-homocysteine +
[protein]-Nomega,Nomega'-dimethyl-L-arginine

Synonyms

At4g31120, EC 2.1.1.124, EC 2.1.1.125, EC 2.1.1.126, EC 2.1.1.23, Hsl7, Jak-binding protein 1, Janus kinase-binding protein 1, JBP1, PRMT-5, PRMT-9, PRMT15, PRMT5, PRMT7, PRMT9, protein arginine methyltransferase 5, Skb1

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.320 type II protein arginine methyltransferase

Expression

Expression on EC 2.1.1.320 - type II protein arginine methyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
curcumin downregulates the PRMT5 expression. Curcumin-mediated signalling events are responsible for its anti-oncogene action against PRMT5
isoform PRMT5 expression is regulated by the circadian clock and responds to both light and temperature cues
PRMT5 expression is down-regulated in senescent and H2O2-treated macrophages rendering ineffectual induction of MHC II transcription by IFN-gamma
PRMT5 protein expression is elevated by 1.8-2.9fold in the denervated tibialis anterior muscle, as compared with the control tibialis anterior muscle
relative to the control muscle PRMT5 mRNA expression levels in the denervated soleus muscle is decreased by 26% after 12 h