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2.1.1.310: 25S rRNA (cytosine2870-C5)-methyltransferase

This is an abbreviated version!
For detailed information about 25S rRNA (cytosine2870-C5)-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
cytosine2870 in 25S rRNA
=
S-adenosyl-L-homocysteine
+
5-methylcytosine2870 in 25S rRNA

Synonyms

m5C-methyltransferase, NOP2, NSUN1/Nol1, p120, proliferation-associated nucleolar antigen, protein p120, RNA:m5C-MTase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.310 25S rRNA (cytosine2870-C5)-methyltransferase

Disease

Disease on EC 2.1.1.310 - 25S rRNA (cytosine2870-C5)-methyltransferase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acquired Immunodeficiency Syndrome
p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas.
Adenocarcinoma
The prognostic significance of proliferation-associated nucleolar protein p120 expression in prostate adenocarcinoma: a comparison with cyclins A and B1, Ki-67, proliferating cell nuclear antigen, and p34cdc2.
Adenocarcinoma of Lung
Expression of nucleolar protein p120 predicts poor prognosis in patients with stage I lung adenocarcinoma.
Prognostic value of nucleolar protein p120 in patients with resected lung adenocarcinoma.
Atherosclerosis
p120 inhibits LPS/TNF?-induced endothelial Ang2 synthesis and release in an NF-?B independent fashion.
Breast Neoplasms
Proliferation-associated nucleolar antigen P120: a prognostic marker in node-negative breast cancer.
Carcinoma
Nucleolar protein p120 expression in oral carcinoma.
p120 and AgNOR nucleolar protein expression: a comparison with nuclear proliferation markers in oral pathology.
Carcinoma, Squamous Cell
p120 and AgNOR nucleolar protein expression: a comparison with nuclear proliferation markers in oral pathology.
Colorectal Neoplasms
Significance of the expression of proliferation-associated nucleolar antigen p120 in human colorectal tumors.
Hemorrhagic Stroke
p120 inhibits LPS/TNF?-induced endothelial Ang2 synthesis and release in an NF-?B independent fashion.
Leukemia
Hydroxylamine cleavage of proteins in polyacrylamide gels.
Localization of the Abelson murine leukemia virus protein in a detergent-insoluble subcellular matrix: architecture of the protein.
Lung Neoplasms
Expression of nucleolar protein p120 in human lung cancer: difference in histological types as a marker for proliferation.
Neoplasms
A conserved motif in the yeast nucleolar protein Nop2p contains an essential cysteine residue.
Analysis of a 17.4 kb DNA segment of yeast chromosome II encompassing the ribosomal protein L19 as well as proteins with homologies to components of the hnRNP and snRNP complexes and to the human proliferation-associated p120 antigen.
Combinatorial effects of monoclonal anti-p120 antibody (MAbp120), liposomes and hyperthermia on MCF-7 and LOX tumor cell lines.
Eukaryotic rRNA Modification by Yeast 5-Methylcytosine-Methyltransferases and Human Proliferation-Associated Antigen p120.
Human proliferation-related protein p120 interacts with HSRP1.
Like p53, the proliferation-associated protein p120 accumulates in human cancer cells following exposure to anticancer drugs.
mRNA levels for human nucleolar protein P120 in tumor and nontumor cells.
Nucleolar and nuclear aberrations in human lox tumor cells following treatment with p120 antisense oligonucleotide ISIS-3466.
Nucleolar protein P120 and its targeting for cancer chemotherapy.
Phosphorylation of the human cell proliferation-associated nucleolar protein p120.
Prognostic value of nucleolar protein p120 in patients with resected lung adenocarcinoma.
Relationship between quantitative expression of protein p120 and proliferative activity in cancer cells.
Significance of the expression of proliferation-associated nucleolar antigen p120 in human colorectal tumors.
The 58-kDa microspherule protein (MSP58), a nucleolar protein, interacts with nucleolar protein p120.
Up-regulation, nuclear import, and tumor growth stimulation of the adhesion protein p120 in pancreatic cancer.
Pancreatic Neoplasms
Up-regulation, nuclear import, and tumor growth stimulation of the adhesion protein p120 in pancreatic cancer.
Sarcoma, Avian
Evidence that there exist four classes of RNA tumor viruses which encode proteins with associated tyrosine protein kinase activities.
Sepsis
p120 inhibits LPS/TNF?-induced endothelial Ang2 synthesis and release in an NF-?B independent fashion.
Vascular Malformations
p120 inhibits LPS/TNF?-induced endothelial Ang2 synthesis and release in an NF-?B independent fashion.