2.1.1.281: phenylpyruvate C3-methyltransferase

This is an abbreviated version!
For detailed information about phenylpyruvate C3-methyltransferase, go to the full flat file.

Reaction

Synonyms

C-MT, ELQ87_35210, MppJ, MT SgvM, phenylpyruvate Cbeta-methyltransferase, phenylpyruvate methyltransferase, S-adenosylmethionine-dependent methyltransferase, SgvM

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.281 phenylpyruvate C3-methyltransferase

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Results	in table
16	AA Sequence
1	Application
3	Cloned(Commentary)
1	Cofactor
1	Crystallization (Commentary)
5	General Information
2	kcat/KM [mM/s]
2	KM Value [mM]
1	Metals/Ions
2	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
6	Organism
1	pH Optimum
10	Protein Variants
2	Purification (Commentary)
3	Reaction
5	Reference
18	Substrates and Products (Substrate)
2	Subunits
13	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
2	Turnover Number [1/s]

Reference

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Reference on EC 2.1.1.281 - phenylpyruvate C3-methyltransferase

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722038

Huang, Y.T.; Lyu, S.Y.; Chuang, P.H.; Hsu, N.S.; Li, Y.S.; Chan, H.C.; Huang, C.J.; Liu, Y.C.; Wu, C.J.; Yang, W.B.; Li, T.L.

In vitro characterization of enzymes involved in the synthesis of nonproteinogenic residue (2S,3S)-beta-methylphenylalanine in glycopeptide antibiotic mannopeptimycin

ChemBioChem

2480-2487

2009

Streptomyces hygroscopicus, Streptomyces hygroscopicus NRRL3085

19731276

735362

Zou, X.W.; Liu, Y.C.; Hsu, N.S.; Huang, C.J.; Lyu, S.Y.; Chan, H.C.; Chang, C.Y.; Yeh, H.W.; Lin, K.H.; Wu, C.J.; Tsai, M.D.; Li, T.L.

Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase

Acta Crystallogr. Sect. D

1549-1560

2014

Streptomyces hygroscopicus (Q643C8), Streptomyces hygroscopicus NRRL3085 (Q643C8)

24914966

755790

Sommer-Kamann, C.; Fries, A.; Mordhorst, S.; Andexer, J.N.; Mueller, M.

Asymmetric C-alkylation by the S-adenosylmethionine-dependent methyltransferase SgvM

Angew. Chem. Int. Ed. Engl.

4033-4036

2017

Streptomyces griseoviridis (A0A3Q9KTF8)

28247461