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2.1.1.269: dimethylsulfoniopropionate demethylase

This is an abbreviated version!
For detailed information about dimethylsulfoniopropionate demethylase, go to the full flat file.

Word Map on EC 2.1.1.269

Reaction

S,S-dimethyl-beta-propiothetin
+
tetrahydrofolate
=
3-(methylsulfanyl)propanoate
+
5-methyltetrahydrofolate

Synonyms

dimethylsufoniopropionate-dependent demethylase A, dimethylsulfoniopropionate demethylase, dimethylsulfoniopropionate methyltransferase, dimethylsulfoniopropionate-dependent demethylase, dimethylsulfoniumpropionate:tetrahydrofolate S-methyltransferase, DmdA, DMSP demethylase, DMSP methyltransferase, DMSP:THF demethylase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.269 dimethylsulfoniopropionate demethylase

Inhibitors

Inhibitors on EC 2.1.1.269 - dimethylsulfoniopropionate demethylase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3-(methylthio)propanoate
-
dimethylsulfoniobutanoate
substrate analog, weak inhibitor
dimethylsulfoniopentanoate
substrate analog, weak inhibitor
methylmercaptopropionate
product inhibition
MgCl2
O2
-
preincubation of the extract under air decreases the activity, 35% loss in 3 h
Propyl iodide
-
0.5 mM, complete inhibition. In the light, the inhibition is far less strong
additional information
-