2.1.1.264: 23S rRNA (guanine2069-N7)-methyltransferase
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For detailed information about 23S rRNA (guanine2069-N7)-methyltransferase, go to the full flat file.
Reaction
Synonyms
3S rRNA m7G2069 methyltransferase, bifunctional methyltransferase, m2G2069 methyltransferase, ribosomal large subunit methyltransferase, rlmK, RlmKL, SAV1081, Smu472, ycbY
ECTree
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Systematic Name
Systematic Name on EC 2.1.1.264 - 23S rRNA (guanine2069-N7)-methyltransferase
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S-adenosyl-L-methionine:23S rRNA (guanine2069-N7)-methyltransferase
The enzyme specifically methylates guanine2069 at position N7 in 23S rRNA. In gamma-proteobacteria the enzyme also catalyses EC 2.1.1.173, 23S rRNA (guanine2445-N2)-methyltransferase, while in beta-proteobacteria the activities are carried out by separate proteins [1]. The enzyme from the gamma-proteobacterium Escherichia coli has RNA unwinding activity as well [1].