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2.1.1.260: rRNA small subunit pseudouridine methyltransferase Nep1

This is an abbreviated version!
For detailed information about rRNA small subunit pseudouridine methyltransferase Nep1, go to the full flat file.

Word Map on EC 2.1.1.260

Reaction

S-adenosyl-L-methionine
+
pseudouridine1191 in yeast 18S rRNA
=
S-adenosyl-L-homocysteine
+
N1-methylpseudouridine1191 in yeast 18S rRNA

Synonyms

Bowen-Conradi syndrome protein, Emg1, Emg1p, essential for mitotic growth 1, N1-specific pseudouridine methyltransferase, Nep1, Nep1 methyltransferase, Nep1p, nucleolar essential protein 1, pseudouridine N1-methyltransferase, pseudouridine-N1-specific methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.260 rRNA small subunit pseudouridine methyltransferase Nep1

Natural Substrates Products

Natural Substrates Products on EC 2.1.1.260 - rRNA small subunit pseudouridine methyltransferase Nep1

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine + pseudouridine1191 in yeast 18S rRNA
S-adenosyl-L-homocysteine + N1-methylpseudouridine1191 in yeast 18S rRNA
show the reaction diagram
additional information
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-
Nep1 target site identification by mass spectrometry, isotope-labeling, and fluorescence anisotropy measurements
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