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2.1.1.260: rRNA small subunit pseudouridine methyltransferase Nep1

This is an abbreviated version!
For detailed information about rRNA small subunit pseudouridine methyltransferase Nep1, go to the full flat file.

Word Map on EC 2.1.1.260

Reaction

S-adenosyl-L-methionine
+
pseudouridine1191 in yeast 18S rRNA
=
S-adenosyl-L-homocysteine
+
N1-methylpseudouridine1191 in yeast 18S rRNA

Synonyms

Bowen-Conradi syndrome protein, Emg1, Emg1p, essential for mitotic growth 1, N1-specific pseudouridine methyltransferase, Nep1, Nep1 methyltransferase, Nep1p, nucleolar essential protein 1, pseudouridine N1-methyltransferase, pseudouridine-N1-specific methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.260 rRNA small subunit pseudouridine methyltransferase Nep1

Inhibitors

Inhibitors on EC 2.1.1.260 - rRNA small subunit pseudouridine methyltransferase Nep1

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
sinefungin
sinefungin binds to Nep1 at a preformed binding site that is topologically equivalent to the cofactor binding site in other SPOUT-class methyltransferases